Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.75 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KDM5C | P41229 | 3/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.47 |
| ▸ | KDM6B | O15054 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL93822 | 1.00 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468618 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL2572722 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL21219028 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468678 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468649 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468630 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL17077298 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL295052 | 0.96 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468680 | 0.96 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113089345-B | Amphoteric polyamine high-molecular polymerization viscose cotton blending leveling agent and preparation method thereof | 苏州联胜化学有限公司 | 2023-05-05 | — | — | CN | claimed |
| US-20110132560-A1 | GYPSUM PRODUCT | KEMIRA OYJ (FI) | 2011-06-09 | — | — | US | claimed |
| EP-2310319-A2 | GYPSUM-FIBRE COMPOSITE PRODUCT AND PAPER COMPRISING SUCH | Kemira OYJ (FI) | 2011-04-20 | — | — | EP | claimed |
| US-20100062255-A1 | GYPSUM PRODUCT AND PROCESS FOR ITS PREPARATION | KEMIRA OYJ (FI) | 2010-03-11 | — | — | US | claimed |
| WO-2010018301-A2 | GYPSUM PRODUCT | KEMIRA OYJ (FI) | 2010-02-18 | — | — | WO | claimed |
| US-20100034727-A1 | PROCESS FOR PRODUCING GYPSUM | KEMIRA OYJ (FI) | 2010-02-11 | — | — | US | claimed |
| EP-2118012-A2 | GYPSUM PRODUCT AND PROCESS FOR ITS PREPARATION | Kemira OYJ (FI) | 2009-11-18 | — | — | EP | claimed |
| EP-2118013-A2 | A PROCESS FOR PRODUCING GYPSUM | Kemira OYJ (FI) | 2009-11-18 | — | — | EP | claimed |
| WO-2008092990-A2 | GYPSUM PRODUCT AND PROCESS FOR ITS PREPARATION | KEMIRA OYJ (FI) | 2008-08-07 | — | — | WO | claimed |
| WO-2008092991-A2 | A PROCESS FOR PRODUCING GYPSUM | KEMIRA OYJ (FI) | 2008-08-07 | — | — | WO | claimed |
| US-20230235253-A1 | CLEANING AGENT COMPOSITION | KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) | 2023-07-27 | — | — | US | disclosed |
| CN-113089345-B | Amphoteric polyamine high-molecular polymerization viscose cotton blending leveling agent and preparation method thereof | 苏州联胜化学有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-107614670-B | Detergent composition in the form of effervescent tablets | 洛雷纳·马提柯马 | 2020-09-01 | — | — | CN | disclosed |
| CN-106460201-B | The non-stained high alkalinity CIP detergent of catalytic type | 艺康美国股份有限公司 | 2019-07-05 | — | — | CN | disclosed |
| EP-2442678-B1 | BEVERAGE PRESERVATIVE SYSTEM CONTAINING PIMARICIN - CYCLODEXTRIN COMPLEX | PEPSICO INC (US) | 2018-05-09 | — | — | EP | disclosed |
| WO-2008092990-A2 | GYPSUM PRODUCT AND PROCESS FOR ITS PREPARATION | KEMIRA OYJ (FI) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008092991-A2 | A PROCESS FOR PRODUCING GYPSUM | KEMIRA OYJ (FI) | 2008-08-07 | — | — | WO | disclosed |
| CN-1973026-A | Amphoteric flourescent whitening agents in detergent formulations | CIBA SC HOLDING AG (CH) | 2007-05-30 | — | — | CN | disclosed |
| CN-1578832-A | Novel alkaline protease variants and detergents and cleansers containing these novel alkaline protease variants | HENKEL KGAA (DE) | 2005-02-09 | — | — | CN | disclosed |
| US-5759982-A | EXTRUDING AN AQUEOUS BLEND COMPRISING ANIONIC SURFACTANT, PHOSPHATE BUILDER AND A POLYETHER PROMOTING THE MELT PROCESSABILITY | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-02 | — | — | US | disclosed |