Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.75 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KDM5C | P41229 | 3/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.47 |
| ▸ | KDM6B | O15054 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL518643 | 1.00 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468618 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL2572722 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL21219028 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468678 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468649 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468630 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL17077298 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL295052 | 0.96 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468680 | 0.96 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260076893-A1 | SELF-FOAMING CLEANSING COMPOSITION | CONOPCO, INC., D/B/A UNILEVER (US) | 2026-03-19 | — | — | US | claimed |
| EP-4586992-A2 | SELF-FOAMING CLEANSING COMPOSITION | Unilever IP Holdings B.V. (NL) | 2025-07-23 | — | — | EP | claimed |
| EP-4586994-A1 | SELF-FOAMING CLEANSING COMPOSITION | Unilever IP Holdings B.V. (NL) | 2025-07-23 | — | — | EP | claimed |
| US-20250222110-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF AGE-RELATED CATARACTS | LIVIONEX INC (US) | 2025-07-10 | — | — | US | claimed |
| US-20250049662-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING VANILLIN OR ONE OF ITS DERIVATIVES, A SPECIFIC SEQUESTERING AGENT, AND POSSIBLY AT LEAST ONE ADDITIONAL ANTIMICROBIAL | L'OREAL (FR) | 2025-02-13 | — | — | US | claimed |
| EP-4216911-B1 | MOISTURIZING ANTIBACTERIAL COMPOSITION | UNILEVER IP HOLDINGS B V (NL) | 2025-01-22 | — | — | EP | claimed |
| US-20240382597-A1 | FORMULATIONS OF ANTI-INFLAMMATORY AGENTS COMPRISING MSM WITH ENHANCED SOLUBILITY IN WATER | LIVIONEX INC (US) | 2024-11-21 | — | — | US | claimed |
| EP-4451876-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING VANILLIN OR ONE OF ITS DERIVATIVES, A SPECIFIC SEQUESTERING AGENT, AND POSSIBLY AT LEAST ONE ADDITIONAL ANTIMICROBIAL | L'OREAL (FR) | 2024-10-30 | — | — | EP | claimed |
| US-20240299279-A1 | TRANSPARENT COSMETIC COMPOSITION WITH ASCORBIC ACID AND A SPECIFIC CATIONIC POLYMER | L'OREAL (FR) | 2024-09-12 | — | — | US | claimed |
| WO-2024133219-A1 | TRANSPARENT COSMETIC COMPOSITION WITH ASCORBIC ACID, A SPECIFIC CATIONIC POLYMER, AND AT LEAST ONE POLYOXYLENATED ALKYLETHER DIMETHYLSILANE COMPOUND | L'OREAL (FR) | 2024-06-27 | — | — | WO | claimed |
| US-5738914-A | EXPOSING THE SUBSTRATE WITH COPPER SULFATE COMPRISING ETHYLENE DIAMINE DISUCCINIC ACID BIODEGRADABLE CHELATE FOR METAL ION TO PREVENT OR REDUCE METAL HYDROXIDE PRECIPITES FORMING | THE ASSOCIATED OCTEL COMPANY LIMITED (GB) | 1998-04-14 | — | — | US | claimed |
| WO-1998000514-A1 | NONAQUEOUS, PARTICULATE-CONTAINING LIQUID DETERGENT COMPOSITIONS WITH SURFACTANT-STRUCTURED LIQUID PHASE | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-08 | — | — | WO | claimed |
| WO-1998000516-A1 | PREPARATION OF NON-AQUEOUS, PARTICULATE-CONTAINING LIQUID DETERGENT COMPOSITIONS WITH SURFACTANT-STRUCTURED LIQUID PHASE | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-08 | — | — | WO | claimed |
| EP-0784669-A1 | PROCESS FOR PREPARING NON-AQUEOUS, BLEACH-CONTAINING LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| EP-0783563-A1 | NONAQUEOUS BLEACH-CONTAINING LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-16 | — | — | EP | claimed |
| WO-1997000938-A1 | NONAQUEOUS, PARTICULATE-CONTAINING LIQUID DETERGENT COMPOSITIONS WITH ALKYL BENZENE SULFONATE SURFACTANT | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-09 | — | — | WO | claimed |
| WO-1996033254-A1 | NONAQUEOUS, PARTICULATE-CONTAINING LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-24 | — | — | WO | claimed |
| EP-0738778-A1 | Nonaqueous, particulate-containing liquid detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1996-10-23 | — | — | EP | claimed |
| WO-1996010072-A1 | PROCESS FOR PREPARING NON-AQUEOUS, BLEACH-CONTAINING LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-04 | — | — | WO | claimed |
| WO-1996010073-A1 | NONAQUEOUS BLEACH-CONTAINING LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-04-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250222110-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF AGE-RELATED CATARACTS | MSMO1, SLC16A8, SMS | LMNA 3443/4885EGLN1 1594/4885ALKBH5 1503/4885 |
| US-20250049662-A1 | AQUEOUS COSMETIC COMPOSITION COMPRISING VANILLIN OR ONE OF ITS DERIVATIVES, A SPECIFIC SEQUESTERING AGENT, AND POSSIBLY AT LEAST ONE ADDITIONAL ANTIMICROBIAL | C1S, VDAC1, DSG1 | LMNA 1593/4885EGLN1 1762/4885ALKBH5 1176/4885 |
| US-20240382597-A1 | FORMULATIONS OF ANTI-INFLAMMATORY AGENTS COMPRISING MSM WITH ENHANCED SOLUBILITY IN WATER | TNF, CD14, CXCL8 | LMNA 2944/4885EGLN1 4730/4885ALKBH5 2463/4885 |
| US-20240299279-A1 | TRANSPARENT COSMETIC COMPOSITION WITH ASCORBIC ACID AND A SPECIFIC CATIONIC POLYMER | GALC, COLGALT1, PROC | LMNA 221/4885EGLN1 2246/4885ALKBH5 1979/4885 |
| US-20260076893-A1 | SELF-FOAMING CLEANSING COMPOSITION | FASN, LSS, LIPA | LMNA 584/4885EGLN1 1119/4885ALKBH5 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.