SCHEMBL5186755

SCHEMBL5186755

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nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.67
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MME P08473 5/20 0.38
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
NFKB1 P19838 1/20 0.34
PTGS2 P35354 1/20 0.34
THPO P40225 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GRN P28799 1/20 0.30
SORT1 Q99523 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5186759 1.00 TGFBR1 (0.67) TGFBR1KDM4EALDH1A1MMEMAPT
SCHEMBL30066898 0.83 TGFBR1 (0.50) TGFBR1KDM4EALDH1A1MMEMAPT
SCHEMBL2553425 0.81 ALDH1A1 (0.52) TGFBR1KDM4EALDH1A1MMEMAPT
SCHEMBL12481793 0.81 ALDH1A1 (0.52) TGFBR1KDM4EALDH1A1MMEMAPT
SCHEMBL28875837 0.80 TGFBR1 (0.47) TGFBR1KDM4EALDH1A1MAPTTHRB
SCHEMBL28875839 0.80 TGFBR1 (0.47) TGFBR1KDM4EALDH1A1MAPTTHRB
SCHEMBL5331603 0.80 TGFBR1 (1.00) TGFBR1KDM4EALDH1A1MMEMAPT
SCHEMBL5891585 0.80 TGFBR1 (1.00) TGFBR1KDM4EALDH1A1MMEMAPT
SCHEMBL29013384 0.79 TGFBR1 (0.48) TGFBR1KDM4EALDH1A1MMEMAPT
SCHEMBL29013382 0.79 TGFBR1 (0.48) TGFBR1KDM4EALDH1A1MMEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed
US-6887657-B2 Silver halide color photographic photosensitive material and image-forming method FUJI PHOTO FILM CO., LTD. (JP) 2005-05-03 US disclosed
US-20050074710-A1 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. 2005-04-07 US disclosed
US-20040234908-A1 Silver halide color photographic photosensitive material and image-forming method FUJI PHOTO FILM CO., LTD. 2004-11-25 US disclosed