Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 1.00 |
| ▸ | MME | P08473 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5891585 | 1.00 | TGFBR1 (1.00) | TGFBR1MMEKDM4EMAPTTHRB | |
| SCHEMBL4442415 | 0.83 | TGFBR1 (0.71) | TGFBR1MMEKDM4EMAPTTHRB | |
| SCHEMBL9984709 | 0.82 | TGFBR1 (0.69) | TGFBR1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL346814 | 0.82 | TGFBR1 (0.69) | TGFBR1MMEKDM4EMAPTTHRB | |
| SCHEMBL5891374 | 0.82 | TGFBR1 (0.69) | TGFBR1MMEKDM4EMAPTTHRB | |
| SCHEMBL9985663 | 0.82 | TGFBR1 (0.69) | TGFBR1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL15451466 | 0.82 | TGFBR1 (0.69) | TGFBR1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL8374365 | 0.82 | TGFBR1 (0.69) | TGFBR1CA2CA1CA12CA9 | |
| SCHEMBL16289815 | 0.81 | TGFBR1 (0.68) | TGFBR1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL8185993 | 0.80 | TGFBR1 (0.67) | TGFBR1MMEKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060329-B | Enzyme response polyamino acid, self-adaptive bionic mechanical gradient hydrogel and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2025-03-07 | — | — | CN | claimed |
| CN-119060329-A | Enzyme response polyamino acid, self-adaptive bionic mechanical gradient hydrogel and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-12-03 | — | — | CN | claimed |
| WO-2005063835-A1 | COBALT IMPRINTED POLYMER COMPOSITION, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | claimed |
| US-20050070677-A1 | Cobalt imprinted polymer composition for selective removal of cobalt, process for preparation thereof, and process for removal of cobalt | COUNCIL OF SCIENTIF AND INDUSTRIAL RESEARCH (IN) | 2005-03-31 | — | — | US | claimed |
| US-20050070676-A1 | Cobalt imprinted polymer composition for selective removal of cobalt, process for preparation thereof, and process for removal of cobalt | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-03-31 | — | — | US | claimed |
| WO-2000069394-A1 | ONE-PART FLUORIDE RELEASING DENTAL MATERIALS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-11-23 | — | — | WO | claimed |
| US-5851546-A | Polymer composition for controlled release of active ingredients in response to pH, and a process of preparing the same | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1998-12-22 | — | — | US | claimed |
| US-5780578-A | Synthetic polymer exhibiting hydrolytic activity, its preparation and use for conversion of esters and amides to the corresponding alcohol and amine | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1998-07-14 | — | — | US | claimed |
| CN-119060329-B | Enzyme response polyamino acid, self-adaptive bionic mechanical gradient hydrogel and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2025-03-07 | — | — | CN | disclosed |
| CN-119060329-A | Enzyme response polyamino acid, self-adaptive bionic mechanical gradient hydrogel and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-12-03 | — | — | CN | disclosed |
| US-20220325072-A1 | ZWITTERIONIC CROSSLINKERS, HYDROGELS COMPRISING ZWITTERIONIC CROSSLINKERS, AND METHODS FOR MAKING AND USING | UNIVERSITY OF IDAHO | 2022-10-13 | — | — | US | disclosed |
| US-9919250-B2 | Filters for oil-water separation having zwitterionic polymers coated or grafted thereon | THE UNIVERSITY OF AKRON (US) | 2018-03-20 | — | — | US | disclosed |
| US-20140209534-A1 | FILTERS FOR OIL-WATER SEPARATION HAVING ZWITTERIONIC POLYMERS COATED OR GRAFTED THEREON | THE UNIVERSITY OF AKRON (US) | 2014-07-31 | — | — | US | disclosed |
| US-20140065226-A1 | THERMO-RESPONSIVE HYDROGEL COMPOSITIONS | BREY ERIC (US) | 2014-03-06 | — | — | US | disclosed |
| WO-2000069394-A1 | ONE-PART FLUORIDE RELEASING DENTAL MATERIALS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| US-6046289-A | FOR INHIBITING COAGULATION OF BLOOD PLATELETS, INHIBITING ADHESION OF ANIMAL CELLS, OR AS SUBSTRATE FOR CULTURING ANIMAL CELLS | FUJIFILM CORPORATION (JP) | 2000-04-04 | — | — | US | disclosed |
| US-5851546-A | Polymer composition for controlled release of active ingredients in response to pH, and a process of preparing the same | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1998-12-22 | — | — | US | disclosed |
| US-5780578-A | Synthetic polymer exhibiting hydrolytic activity, its preparation and use for conversion of esters and amides to the corresponding alcohol and amine | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 1998-07-14 | — | — | US | disclosed |
| EP-0488258-B1 | Propenamide derivatives, polymers, copolymers and use thereof | FUJI PHOTO FILM CO LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| EP-0488258-A2 | Propenamide derivatives, polymers, copolymers and use thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220325072-A1 | ZWITTERIONIC CROSSLINKERS, HYDROGELS COMPRISING ZWITTERIONIC CROSSLINKERS, AND METHODS FOR MAKING AND USING | ASS1, GFER, ASIC1 | TGFBR1 126/4885MME 4353/4885KDM4E 1832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.