Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.71 |
| ▸ | RARB | P10826 | 4/20 | 0.68 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.64 |
| ▸ | THRA | P10827 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7332274 | 0.99 | TSHR (0.71) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL7339141 | 0.99 | TSHR (0.76) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| Hydrochloric Acid SCHEMBL6539254 | 0.97 | TSHR (0.74) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| Hydrochloric Acid SCHEMBL7334829 | 0.97 | TSHR (0.74) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| Hydrochloric Acid SCHEMBL7330237 | 0.97 | TSHR (0.74) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| Hydrochloric Acid SCHEMBL7339554 | 0.88 | TSHR (0.60) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL6538491 | 0.87 | TSHR (0.62) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL7331983 | 0.87 | TSHR (0.59) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL7333300 | 0.87 | TSHR (0.59) | TSHRTP53PLA2G4BRARBPLA2G4A | |
| SCHEMBL503727 | 0.87 | TP53 (0.96) | TSHRTP53PLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285619-B2 | Echinocandin derivatives, their method of preparation and their application as anti-fungal agents | AVENTIS PHARMA S.A. (FR) | 2007-10-23 | — | — | US | disclosed |
| US-7160983-B2 | Echinocandin derivatives, their method of preparation and their application as anti-fungal agents | AVENTIS PHARMA S.A. (FR) | 2007-01-09 | — | — | US | disclosed |
| US-20050267019-A1 | Echinocandin derivatives, their method of preparation and their application as anti-fungal agents | NOVEXEL (FR) | 2005-12-01 | — | — | US | disclosed |
| US-20040072737-A1 | 1((-4-oxo- N2-(12-methyl-1-oxotetradecyl) L-ornithine) 4-(4-(4- hydroxyphenyl)-L-threonine)-5-L-serine-echinocandin B, and other derivatives | AVENTIS PHARMA S.A. | 2004-04-15 | — | — | US | disclosed |
| US-6677429-B1 | FUNGICIDES SUCH AS 1-((S)-N2-(12-METHYL-1-OXOTETRADECYL)-4-(((3-PIPERIDINYL)OXY)IMINO)-L -ORNITHINE)4-((4-HYDROXYPHENYL)-L -THREONINE)-5-L-SERINE AND ISOMERS ADMINISTERING TO MAMMALS AS ANTIPROLIFERATIVE AGENTS FOR CANDIDA | AVENTIS PHARMA S.A. (FR) | 2004-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072737-A1 | 1((-4-oxo- N2-(12-methyl-1-oxotetradecyl) L-ornithine) 4-(4-(4- hydroxyphenyl)-L-threonine)-5-L-serine-echinocandin B, and other derivatives | ODC1, OAT, DPM1 | TSHR 4684/4885TP53 1649/4885PLA2G4B 1254/4885 |
| US-20050267019-A1 | Echinocandin derivatives, their method of preparation and their application as anti-fungal agents | ERG28, DPM1, CYP51A1 | TSHR 4662/4885TP53 3425/4885PLA2G4B 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.