Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311985 | 0.86 | KMT2A (0.75) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL8619629 | 0.86 | MAPK1 (0.60) | HTTNPC1RAB9AHPGD | |
| SCHEMBL2317149 | 0.85 | HTT (0.88) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL28833417 | 0.85 | MEN1 (0.77) | MEN1KMT2A | |
| SCHEMBL12535510 | 0.84 | MEN1 (0.54) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL14085811 | 0.84 | ALDH1A1 (0.67) | KMT2AHTTPOLBHPGD | |
| SCHEMBL300285 | 0.83 | KMT2A (0.66) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL29554472 | 0.83 | KMT2A (0.66) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL6072206 | 0.82 | KMT2A (0.70) | MEN1KMT2AHTTNPC1RAB9A | |
| SCHEMBL1272337 | 0.82 | KMT2A (0.70) | MEN1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096333-A | NITROSATION OF A 2-METHYLACETANILIDE | TENNECO CHEMICALS, INC. (US) | 1978-06-20 | — | — | US | claimed |
| US-3988347-A | NITROSATION OF A 2-METHYL-ACETANILIDE WITH SODIUM NITRITE | TENNECO CHEMICALS, INC. (US) | 1976-10-26 | — | — | US | claimed |
| CN-112430216-B | Preparation method of benzimidazole compound in pesticide | 六夫丁作物保护有限公司 | 2022-12-09 | — | — | CN | disclosed |
| WO-2021254529-A1 | BICYCLIC COMPOUND | 江苏先声药业有限公司 | 2021-12-23 | — | — | WO | disclosed |
| CN-112430216-A | Preparation method of benzimidazole compound in pesticide and pesticide | 苏州帆木云智能科技有限公司 | 2021-03-02 | — | — | CN | disclosed |
| WO-2017040304-A1 | MALT1 INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-03-09 | — | — | WO | disclosed |
| US-8940724-B2 | Quinoline derivitives and their uses | AMGEN INC. (US) | 2015-01-27 | — | — | US | disclosed |
| US-8168654-B2 | Quinuclidine derivatives binding to mucarinic M3 receptors | NOVARTIS AG (CH) | 2012-05-01 | — | — | US | disclosed |
| US-8168654-B2 | Quinuclidine derivatives binding to mucarinic M3 receptors | NOVARTIS AG (CH) | 2012-05-01 | — | — | US | disclosed |
| US-20100331293-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-7732416-B2 | For protecting plants against parasitic feeding pests; also against the infestation of pets, especially cats and dogs, by fleas, ticks and nematodes; pesticides for crop protection | MERIAL LIMITED (US) | 2010-06-08 | — | — | US | disclosed |
| US-20100041887-A1 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | COLLINGWOOD STEPHEN PAUL | 2010-02-18 | — | — | US | disclosed |
| US-20100041887-A1 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | COLLINGWOOD STEPHEN PAUL | 2010-02-18 | — | — | US | disclosed |
| US-7605134-B2 | Pesticides | MERIAL LIMITED (US) | 2009-10-20 | — | — | US | disclosed |
| EP-1594878-B1 | AVERMECTIN MONOSACCHARIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | MERIAL LTD (GB) | 2008-06-04 | — | — | EP | disclosed |
| EP-1804785-A2 | DIARYL UREAS AS CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2007-07-11 | — | — | EP | disclosed |
| US-20070060563-A1 | Quinuclidine derivatives binding to mucarinic m3 receptors | NOVARTIS AG (CH) | 2007-03-15 | — | — | US | disclosed |
| US-20070060563-A1 | Quinuclidine derivatives binding to mucarinic m3 receptors | NOVARTIS AG (CH) | 2007-03-15 | — | — | US | disclosed |
| WO-2006049941-A2 | DIARYL UREAS AS CB1 ANTAGONISTS | NEUROGEN CORPORATION (US) | 2006-05-11 | — | — | WO | disclosed |
| US-4096333-A | NITROSATION OF A 2-METHYLACETANILIDE | TENNECO CHEMICALS, INC. (US) | 1978-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060563-A1 | Quinuclidine derivatives binding to mucarinic m3 receptors | CHRM3, CHRM2, CHRM1 | MEN1 903/4885KMT2A 2755/4885HTT 4255/4885 |
| US-20100041887-A1 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | CHRM3, CHRM2, CHRM1 | MEN1 903/4885KMT2A 2755/4885HTT 4255/4885 |
| US-20100331293-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | MCL1, MALT1, BCL9 | MEN1 1533/4885KMT2A 880/4885HTT 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.