Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340222 | 0.88 | CCR8 (0.78) | SNCACCR8MEN1KMT2AMAPT | |
| SCHEMBL5188604 | 0.85 | LMNA (0.68) | CCR8MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5188667 | 0.83 | CCR8 (0.63) | SNCACCR8MEN1KMT2AMAPT | |
| SCHEMBL5669631 | 0.80 | GAA (0.61) | SNCAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2061754 | 0.79 | ALOX5 (0.77) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL2633343 | 0.79 | ALOX5 (0.77) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9423776 | 0.78 | ALOX5 (0.75) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL13265822 | 0.78 | LMNA (0.58) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL1337665 | 0.78 | CCR8 (0.89) | CCR8MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1339700 | 0.77 | CCR8 (0.93) | CCR8MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421057-A4 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA PTY LTD (AU) | 2007-03-14 | — | — | EP | claimed |
| US-20050038248-A1 | Chemotherapeutic agents | STARPHARMA PTY LTD (AU) | 2005-02-17 | — | — | US | claimed |
| EP-1421057-A1 | CHEMOTHERAPEUTIC AGENTS | Starpharma Limited (AU) | 2004-05-26 | — | — | EP | claimed |
| WO-2003018536-A1 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA LIMITED (AU) | 2003-03-06 | — | — | WO | claimed |
| EP-1421057-A4 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA PTY LTD (AU) | 2007-03-14 | — | — | EP | disclosed |
| US-20050038248-A1 | Chemotherapeutic agents | STARPHARMA PTY LTD (AU) | 2005-02-17 | — | — | US | disclosed |
| EP-1421057-A1 | CHEMOTHERAPEUTIC AGENTS | Starpharma Limited (AU) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003018536-A1 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA LIMITED (AU) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038248-A1 | Chemotherapeutic agents | MKI67, PCNA, MCL1 | SNCA 4371/4885CCR8 511/4885MEN1 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.