Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | CCR8 | P51685 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188667 | 0.86 | CCR8 (0.63) | LMNASMN1; SMN2HPGDCCR8MEN1 | |
| SCHEMBL5187445 | 0.85 | SNCA (0.59) | LMNASMN1; SMN2HPGDCCR8MEN1 | |
| SCHEMBL8627623 | 0.81 | F10 (0.64) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL27181622 | 0.81 | KMT2A (0.75) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL27180643 | 0.81 | KMT2A (0.75) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL1337665 | 0.81 | CCR8 (0.89) | LMNASMN1; SMN2HPGDCCR8MEN1 | |
| SCHEMBL1339700 | 0.81 | CCR8 (0.93) | LMNASMN1; SMN2HPGDCCR8MEN1 | |
| SCHEMBL11698871 | 0.78 | CA2 (0.71) | SMN1; SMN2KMT2AALDH1A1NPC1F10 | |
| SCHEMBL6403077 | 0.78 | KMT2A (0.81) | LMNASMN1; SMN2HPGDCCR8MEN1 | |
| SCHEMBL5187417 | 0.78 | CCR8 (0.52) | LMNASMN1; SMN2HPGDCCR8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421057-A4 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA PTY LTD (AU) | 2007-03-14 | — | — | EP | claimed |
| US-20050038248-A1 | Chemotherapeutic agents | STARPHARMA PTY LTD (AU) | 2005-02-17 | — | — | US | claimed |
| EP-1421057-A1 | CHEMOTHERAPEUTIC AGENTS | Starpharma Limited (AU) | 2004-05-26 | — | — | EP | claimed |
| WO-2003018536-A1 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA LIMITED (AU) | 2003-03-06 | — | — | WO | claimed |
| EP-1421057-A4 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA PTY LTD (AU) | 2007-03-14 | — | — | EP | disclosed |
| US-20050038248-A1 | Chemotherapeutic agents | STARPHARMA PTY LTD (AU) | 2005-02-17 | — | — | US | disclosed |
| EP-1421057-A1 | CHEMOTHERAPEUTIC AGENTS | Starpharma Limited (AU) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003018536-A1 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA LIMITED (AU) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038248-A1 | Chemotherapeutic agents | MKI67, PCNA, MCL1 | LMNA 3779/4885SMN1; SMN2 2728/4885HPGD 713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.