SCHEMBL51879

SCHEMBL51879

O=C1CCc2cc(Cl)ccc2S1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
VHL P40337 1/20 0.43
ELOC Q15369 1/20 0.43
ELOB Q15370 1/20 0.43
F7 P08709 1/20 0.40
PARP1 P09874 1/20 0.40
F3 P13726 1/20 0.40
PARP10 Q53GL7 1/20 0.40
MAPT P10636 3/20 0.39
MEN1 O00255 2/20 0.39
GAA P10253 2/20 0.39
KMT2A Q03164 2/20 0.39
SRD5A1 P18405 5/20 0.39
SRD5A2 P31213 2/20 0.39
AHR P35869 2/20 0.38
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
METAP1 P53582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9700006 0.82 HPGD (0.50) HPGDL3MBTL1VHLELOCELOB
SCHEMBL28705640 0.81 ALDH1A1 (0.45) LMNA
SCHEMBL8561388 0.77 PARP10 (0.43) L3MBTL1PARP1PARP10SRD5A1SRD5A2
SCHEMBL566630 0.77 PARP1 (0.40) PARP1PARP10SRD5A1NOTUM
SCHEMBL11520308 0.77 PARP10 (0.43) HPGDPARP1PARP10MAPTMEN1
SCHEMBL11753994 0.77 HPGD (0.57) HPGDL3MBTL1MAPTMEN1KMT2A
SCHEMBL28361892 0.76 TYMS (0.31) TYMS
SCHEMBL9024306 0.73 TYMS (0.35) TYMS
SCHEMBL6238887 0.71 ALDH1A1 (0.47) HPGDL3MBTL1PARP1PARP10MAPT
SCHEMBL29836089 0.71 ALDH1A1 (0.47) HPGDL3MBTL1PARP1PARP10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110862401-B Method for preparing spiro indole derivative by basic ionic liquid one-pot method 马鞍山市泰博化工科技有限公司 2021-05-14 CN claimed
CN-110862401-A Method for preparing spiro indole derivative by basic ionic liquid one-pot method 马鞍山市泰博化工科技有限公司 2020-03-06 CN claimed
CN-110862401-B Method for preparing spiro indole derivative by basic ionic liquid one-pot method 马鞍山市泰博化工科技有限公司 2021-05-14 CN disclosed
CN-110862401-A Method for preparing spiro indole derivative by basic ionic liquid one-pot method 马鞍山市泰博化工科技有限公司 2020-03-06 CN disclosed
EP-2192163-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2017-04-19 EP disclosed
EP-2053095-B2 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2017-02-22 EP disclosed
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8557889-B2 Ink composition and inkjet recording method FUJIFILM CORPORATION (JP) 2013-10-15 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2192163-A1 Ink composition and inkjet recording method Fujifilm Corporation (JP) 2010-06-02 EP disclosed
US-20100129565-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-05-27 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
WO-1998009969-A1 NOVEL ARYL-PYRIDAZINES ASTRA PHARMACEUTICALS LTD. (GB) 1998-03-12 WO disclosed
US-4134813-A THIOCHROMANONES, AMINE BASF AKTIENGESELLSCHAFT (DE) 1979-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 HPGD 2563/4885L3MBTL1 2764/4885VHL 3930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.