Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186531 | 0.90 | LMNA (0.41) | LMNAALDH1A1HTR2C | |
| SCHEMBL5728259 | 0.88 | — | — | |
| SCHEMBL9847790 | 0.85 | HTR2C (0.39) | LMNAALDH1A1HTR2C | |
| SCHEMBL17878534 | 0.78 | CA1 (0.38) | CTSKLMNACA1CA2ALDH1A1 | |
| SCHEMBL646201 | 0.77 | PAM (0.38) | LMNACA1CA2ALDH1A1HTR2C | |
| SCHEMBL5187658 | 0.77 | GPR84 (0.48) | LMNA | |
| SCHEMBL7705563 | 0.76 | TSHR (0.38) | LMNAHTR2C | |
| SCHEMBL27952449 | 0.75 | CA1 (0.33) | LMNACA1 | |
| SCHEMBL21239299 | 0.74 | KDM4C (0.34) | LMNACA1 | |
| SCHEMBL24580161 | 0.74 | TDP1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1760067-A2 | Compounds with protected hydroxy groups | Givaudan SA (CH) | 2007-03-07 | — | — | EP | disclosed |