Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | STS | P08842 | 5/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12364241 | 0.81 | HSD17B1 (0.67) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL5024255 | 0.81 | HSD17B1 (0.67) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL2244884 | 0.81 | HSD17B1 (0.67) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL14421698 | 0.81 | HSD17B1 (0.67) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL6535977 | 0.81 | HSD17B1 (0.67) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL14558089 | 0.80 | LMNA (0.52) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL5191077 | 0.80 | LMNA (0.52) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL5189524 | 0.78 | LMNA (0.47) | LMNAMAPTRECQLSMN1; SMN2KDM4E | |
| SCHEMBL6466520 | 0.75 | LMNA (0.51) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL5024866 | 0.73 | HSD17B1 (0.62) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042352-B1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | RES TRIANGLE INST (US) | 2007-07-25 | — | — | EP | disclosed |
| US-6864248-B2 | Androgenic steroid compounds and a method of making and using the same | RESEARCH TRIANGLE INSTITUTE (US) | 2005-03-08 | — | — | US | disclosed |
| US-20040097477-A1 | Androgenic steroid compounds and a method of making and using the same | RESEARCH TRIANGLE INSTITUTE (US) | 2004-05-20 | — | — | US | disclosed |
| US-6670352-B2 | E.g. 7alpha,11beta-dimethyl-17beta-hydroxyestr-4-en-3-one; controlling male fertility; stereospecific synthesis starting from adrenosterone, and introducing the 7alpha substituent prior to an 11-substituent | RESEARCH TRIANGLE INSTITUTE | 2003-12-30 | — | — | US | disclosed |
| US-20020103177-A1 | Androgenic steroid compounds and a method of making and using the same | COOK C EDGAR (US) | 2002-08-01 | — | — | US | disclosed |
| US-6369047-B2 | ESTR-4-EN-3-ONE DERIVATIVES WITH ENHANCED ACTIVITY RELATIVE TO TESTOSTERONE DUE TO ENHANCED POTENCY; REDUCTION IN SIZE OF SKIN PATCHES | RESEARCH TRIANGLE INSTITUTE | 2002-04-09 | — | — | US | disclosed |
| US-20020002156-A1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | COOK C EDGAR (US) | 2002-01-03 | — | — | US | disclosed |
| US-5952319-A | CONTROLLING MALE FERTILITY IN MAMMAL | RESEARCH TRIANGLE INSTITUTE (US) | 1999-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002156-A1 | ANDROGENIC STEROID COMPOUNDS AND A METHOD OF MAKING AND USING THE SAME | NR5A1, CYP17A1, SHBG | LMNA 1964/4885MAPT 4047/4885HSD17B1 17/4885 |
| US-20040097477-A1 | Androgenic steroid compounds and a method of making and using the same | NR5A1, CYP17A1, SHBG | LMNA 1964/4885MAPT 4047/4885HSD17B1 17/4885 |
| US-20020103177-A1 | Androgenic steroid compounds and a method of making and using the same | NR5A1, CYP17A1, SHBG | LMNA 1964/4885MAPT 4047/4885HSD17B1 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.