Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23141111 | 0.79 | PGR (0.53) | CCR8MEN1KMT2ANPC1BCL2L1 | |
| SCHEMBL5187428 | 0.78 | PGR (0.64) | CCR8MEN1KMT2ABCL2L1MCL1 | |
| SCHEMBL5188604 | 0.78 | LMNA (0.68) | CCR8MEN1KMT2ANPC1LMNA | |
| SCHEMBL5188667 | 0.78 | CCR8 (0.63) | CCR8MEN1KMT2ANPC1LMNA | |
| SCHEMBL1342005 | 0.77 | SMN1; SMN2 (0.61) | MEN1KMT2ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28841732 | 0.76 | KEAP1 (0.70) | KMT2ALMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23141057 | 0.76 | ALDH1A1 (0.59) | MEN1KMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL5187445 | 0.74 | SNCA (0.59) | CCR8MEN1KMT2ANPC1LMNA | |
| SCHEMBL7079519 | 0.74 | MEN1 (0.58) | MEN1KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL2880191 | 0.73 | LMNA (0.54) | MEN1KMT2ANPC1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421057-A4 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA PTY LTD (AU) | 2007-03-14 | — | — | EP | claimed |
| US-20050038248-A1 | Chemotherapeutic agents | STARPHARMA PTY LTD (AU) | 2005-02-17 | — | — | US | claimed |
| EP-1421057-A1 | CHEMOTHERAPEUTIC AGENTS | Starpharma Limited (AU) | 2004-05-26 | — | — | EP | claimed |
| WO-2003018536-A1 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA LIMITED (AU) | 2003-03-06 | — | — | WO | claimed |
| EP-1421057-A4 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA PTY LTD (AU) | 2007-03-14 | — | — | EP | disclosed |
| US-20050038248-A1 | Chemotherapeutic agents | STARPHARMA PTY LTD (AU) | 2005-02-17 | — | — | US | disclosed |
| EP-1421057-A1 | CHEMOTHERAPEUTIC AGENTS | Starpharma Limited (AU) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003018536-A1 | CHEMOTHERAPEUTIC AGENTS | STARPHARMA LIMITED (AU) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038248-A1 | Chemotherapeutic agents | MKI67, PCNA, MCL1 | CCR8 511/4885MEN1 2211/4885KMT2A 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.