SCHEMBL518877

SCHEMBL518877

c1cnc2c(c1)ccc1ncc3ccc4c(ccc5[nH]cnc54)c3c12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 3/20 0.38
KDM4E B2RXH2 3/20 0.38
CCR1 P32246 3/20 0.38
CCR5 P51681 3/20 0.38
CCR8 P51685 3/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP3A4 P08684 2/20 0.38
ALDH1A1 P00352 1/20 0.38
PRNP P04156 1/20 0.38
HPGD P15428 1/20 0.38
GMNN O75496 1/20 0.38
TP53 P04637 1/20 0.38
HSP90AA1 P07900 1/20 0.38
MMP2 P08253 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10787406 0.90 LMNA (0.43) LMNAMEN1KMT2APOLBMAPT
SCHEMBL18040135 0.89 LMNA (0.40) LMNAMEN1KMT2APOLBMAPT
SCHEMBL4992901 0.82 LMNA (0.58) LMNAMEN1KMT2APOLBMAPT
SCHEMBL29599662 0.79 MEN1 (0.49) LMNAMEN1KMT2APOLBMAPT
SCHEMBL14127595 0.79 MEN1 (0.49) LMNAMEN1KMT2APOLBMAPT
SCHEMBL11369703 0.79 KDM4E (0.42) LMNAMAPTKDM4ECCR1CCR5
Benzimidazole SCHEMBL27609877 0.76 LMNA (0.43) LMNAKMT2APOLBMAPTKDM4E
Benzimidazole SCHEMBL27508243 0.76 LMNA (0.43) LMNAKMT2APOLBMAPTKDM4E
SCHEMBL9374144 0.74 LMNA (0.64) LMNAMEN1KMT2APOLBMAPT
SCHEMBL1853777 0.72 LMNA (0.44) LMNAMAPTKDM4ECCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12593527-B2 Binary colloidal quantum dot technology NEW JERSEY INSTITUTE OF TECHNOLOGY (US) 2026-03-31 US claimed
WO-2025262667-A1 POTENTIOMETRIC‑ ORGANIC ELECTROCHEMICAL TRANSISTORS (POECT), METHODS OF MAKING AND USES THEREOF KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2025-12-26 WO claimed
WO-2025224151-A1 SINGLE ORGANIC ELECTROCHEMICAL NEURON CAPABLE OF ANTICOINCIDENCE DETECTION PADINHARE HARIKESH (SE) 2025-10-30 WO claimed
US-12364155-B2 Polymer compositions for vertical channel organic electrochemical transistors and complementary logic circuits NORTHWESTERN UNIVERSITY (US) 2025-07-15 US claimed
US-20250098393-A1 MONOLITHIC INTEGRATION OF VERTICAL ELECTROCHEMICAL TRANSISTORS NORTHWESTERN UNIVERSITY 2025-03-20 US claimed
WO-2025051741-A1 A METHOD OF CHANGE CARRIER DENSITY AND AN ELECTRONIC DEVICE MANUFACTURED ACCORDING TO SAID METHOD CAMBRIDGE ENTERPRISE LIMITED (GB) 2025-03-13 WO claimed
US-20250063880-A1 ANTI-AMBIPOLAR BILAYER ORGANIC ELECTROCHEMICAL TRANSISTORS NORTHWESTERN UNIVERSITY (US) 2025-02-20 US claimed
US-20240405368-A1 Hybrid Separator Comprising Ceramic-Coated Thermally Stable Polymer Fibers for a Lithium Battery or Sodium Battery and Manufacturing Method HONEYCOMB BATTERY COMPANY (US) 2024-12-05 US claimed
US-20240405296-A1 Thermally Stable Hybrid Separator for a Lithium Battery or Sodium Battery and Manufacturing Method HONEYCOMB BATTERY COMPANY (US) 2024-12-05 US claimed
WO-2024250001-A1 HYBRID SEPARATOR COMPRISING CERAMIC-COATED THERMALLY STABLE POLYMER FIBERS FOR A LITHIUM BATTERY OR SODIUM BATTERY AND MANUFACTURING METHOD HONEYCOMB BATTERY COMPANY (US) 2024-12-05 WO claimed
US-6605904-B2 Tunable multicolor electroluminescent device UNIVERSITY OF ROCHESTER 2003-08-12 US claimed
US-20020097001-A1 Tunable multicolor electroluminescent device NATIONAL SCIENCE FOUNDATION 2002-07-25 US claimed
US-5858561-A ELECTROLUMINESCENT ORGANIC LIGHT EMITTING MATERIAL BETWEEN TWO ELECTRICALLY INSULATING MATERIALS, EACH IN CONTACT WITH ELECTRODE CONNECTED TO VOLTAGE SOURCE THE OHIO STATE UNIVERSITY (US) 1999-01-12 US claimed
EP-0815598-A1 BIPOLAR ELECTROLUMINESCENT DEVICE The Ohio State University (US) 1998-01-07 EP claimed
EP-0812260-A1 BIPOLAR ELECTROLUMINESCENT DEVICE The Ohio State University (US) 1997-12-17 EP claimed
US-5663573-A Bipolar electroluminescent device THE OHIO STATE UNIVERSITY (US) 1997-09-02 US claimed
WO-1996029747-A1 BIPOLAR ELECTROLUMINESCENT DEVICE THE OHIO STATE UNIVERSITY (US) 1996-09-26 WO claimed
WO-1996026830-A1 BIPOLAR ELECTROLUMINESCENT DEVICE THE OHIO STATE UNIVERSITY (US) 1996-09-06 WO claimed
US-5114610-A Lewis acids dissolved in aprotic organic solvents HONEYWELL INC. (US) 1992-05-19 US claimed
US-4620942-A DOPED BENZIMIDAZOBENZOPHENANTHROLINE LADDER POLYMER THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1986-11-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12593527-B2 Binary colloidal quantum dot technology DYRK1B, CRYAB, IGF2BP2 LMNA 4850/4885MEN1 3335/4885KMT2A 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.