SCHEMBL5189223

SCHEMBL5189223

CCC1=Cc2c(-c3ccccc3)cccc2C1[Hf](C)CC[Hf](C)C1C(CC)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5190938 0.84
SCHEMBL5189632 0.83 PDCD1 (0.38) PDCD1CD274DPP4
SCHEMBL5189192 0.83 HTR7 (0.33)
SCHEMBL7635065 0.83 BCHE (0.33) PDCD1CD274
Hydrochloric Acid SCHEMBL7217378 0.81
SCHEMBL5859122 0.78 PDCD1 (0.34) PDCD1CD274DPP4
SCHEMBL6649301 0.77 PDCD1 (0.33) PDCD1CD274DPP4
SCHEMBL7644720 0.77 PDCD1 (0.33) PDCD1CD274DPP4
SCHEMBL4620494 0.77 PDCD1 (0.33) PDCD1CD274DPP4
SCHEMBL1582945 0.77 PDCD1 (0.37) PDCD1CD274DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0824113-B2 Supported catalyst, process for its preparation and its use in olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2012-06-27 EP disclosed
EP-0811627-B1 Neutral or ionic compound suitable as catalyst component for olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2007-07-25 EP disclosed
EP-0824112-B1 Supported chemical compound BASELL POLYOLEFINE GMBH (DE) 2006-05-10 EP disclosed
EP-0824113-B1 Supported catalyst, process for its preparation and its use in olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2001-06-20 EP disclosed
EP-0824112-A1 Supported chemical compound HOECHST AKTIENGESELLSCHAFT (DE) 1998-02-18 EP disclosed
EP-0824113-A1 Supported catalyst, process for its preparation and its use in olefin polymerization HOECHST AKTIENGESELLSCHAFT (DE) 1998-02-18 EP disclosed
EP-0811627-A2 Neutral or ionic compound suitable as catalyst component for olefin polymerization HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-10 EP disclosed