Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.57 |
| ▸ | CTSL | P07711 | 3/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18775057 | 0.91 | CTSS (0.57) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL18775053 | 0.91 | CTSS (0.57) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL13863699 | 0.91 | CTSS (0.57) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL18020341 | 0.89 | CTSS (0.55) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL15774022 | 0.89 | KYNU (0.56) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL3044553 | 0.88 | CTSS (0.70) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL4837883 | 0.88 | KYNU (0.55) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL4837891 | 0.88 | KYNU (0.55) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL16346611 | 0.87 | KYNU (0.59) | KYNUCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL1198823 | 0.86 | KYNU (0.56) | KYNUCTSLCTSSCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531507-B2 | Acylated nonadepsipeptides containing pyridyl alanine residues | AICURIS GMBH & CO. KG (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7531507-B2 | Acylated nonadepsipeptides containing pyridyl alanine residues | AICURIS GMBH & CO. KG (DE) | 2009-05-12 | — | — | US | disclosed |
| EP-1807443-A1 | ACYLATED NONADEPSIPEPTIDES USED AS LYSOBACTIN DERIVATIVES | AiCuris GmbH & Co. KG (DE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006048139-A1 | ACYLATED NONADEPSIPEPTIDES USED AS LYSOBACTIN DERIVATIVES | AICURIS GMBH & CO. KG (DE) | 2006-05-11 | — | — | WO | disclosed |