Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.68 |
| ▸ | ESR1 | P03372 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.68 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | STS | P08842 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylparaben SCHEMBL830283 | 0.92 | ALDH1A1 (0.66) | TSHRESR1LMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL1131653 | 0.90 | ESR1 (0.55) | TSHRESR1LMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL28236585 | 0.90 | TSHR (0.55) | TSHRESR1LMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL27700689 | 0.89 | TSHR (0.54) | TSHRESR1LMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL3832690 | 0.86 | TSHR (0.50) | TSHRESR1LMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL27799739 | 0.85 | ESR1 (0.87) | TSHRESR1LMNACYP1A2CYP2C19 | |
| Butylparaben SCHEMBL28872721 | 0.85 | ESR1 (0.93) | TSHRESR1LMNACYP1A2CYP2C19 | |
| Propylparaben SCHEMBL8509467 | 0.85 | ESR1 (0.56) | TSHRESR1LMNACYP1A2CYP2C19 | |
| Nonyl 4-Hydroxybenzoate SCHEMBL28216412 | 0.84 | TSHR (0.59) | TSHRESR1LMNACYP1A2CYP2C19 | |
| SCHEMBL28842646 | 0.83 | ADRB2 (0.52) | TSHRESR1LMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809309-A1 | TOPICAL COMPOSITIONS COMPRISING MYRICA GALE OIL | The Boots Company PLC (GB) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006051246-A1 | TOPICAL COMPOSITIONS COMPRISING MYRICA GALE OIL | THE BOOTS COMPANY PLC (GB) | 2006-05-18 | — | — | WO | disclosed |
| WO-2000074636-A1 | METHODS FOR TREATING SKIN WITH 3-HYDROXY BENZOIC ACID AND RELATED COMPOSITIONS | REVLON CONSUMER PRODUCTS CORPORATION (US) | 2000-12-14 | — | — | WO | disclosed |
| WO-1996033773-A2 | IMPROVEMENTS IN OR RELATING TO COSMETIC TREATMENT OF SKIN LINES | OLAVESEN LIMITED (GB) | 1996-10-31 | — | — | WO | disclosed |