Propylparaben

Propylparaben

SCHEMBL830283

CC(O)Oc1ccccc1.CCCOC(=O)c1ccc(O)cc1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.66
ESR1 P03372 4/20 0.66
TSHR P16473 3/20 0.66
TDP1 Q9NUW8 2/20 0.66
CHRM1 P11229 1/20 0.66
SLC6A2 P23975 1/20 0.66
KDR P35968 1/20 0.66
LMNA P02545 3/20 0.59
SMN1; SMN2 Q16637 4/20 0.55
MAPK1 P28482 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C19 P33261 1/20 0.55
NR1H2 P55055 1/20 0.55
RNASEL Q05823 1/20 0.55
MAPT P10636 5/20 0.53
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
THRB P10828 1/20 0.53
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylparaben SCHEMBL5189352 0.92 TSHR (0.68) ALDH1A1ESR1TSHRTDP1CHRM1
Propylparaben SCHEMBL8509467 0.92 ESR1 (0.56) ALDH1A1ESR1TSHRTDP1CHRM1
Propylparaben SCHEMBL8396726 0.88 MAPT (0.51) ALDH1A1ESR1TSHRTDP1CHRM1
Butylparaben SCHEMBL1131653 0.88 ESR1 (0.55) ALDH1A1ESR1TSHRTDP1CHRM1
SCHEMBL28842646 0.85 ADRB2 (0.52) ALDH1A1ESR1TSHRTDP1CHRM1
Propylparaben SCHEMBL10582852 0.84 ESR1 (0.86) ALDH1A1ESR1TSHRTDP1CHRM1
Propylparaben SCHEMBL1903370 0.84 ALDH1A1 (0.86) ALDH1A1ESR1TSHRTDP1CHRM1
Butylparaben SCHEMBL3832690 0.84 TSHR (0.50) ALDH1A1ESR1TSHRTDP1CHRM1
Propylparaben SCHEMBL9415720 0.84 ESR1 (0.69) ALDH1A1ESR1TSHRTDP1CHRM1
Butylparaben SCHEMBL28236585 0.83 TSHR (0.55) ALDH1A1ESR1TSHRTDP1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4021392-A1 A PACKAGED HAIR CARE COMPOSITION The Procter & Gamble Company (US) 2022-07-06 EP disclosed
CN-111658611-B Vaccine delivery system based on microemulsion, and preparation method and application thereof 四川大学 2021-06-01 CN disclosed
US-20210059926-A1 PACKAGED HAIR CARE COMPOSITION THE PROCTER & GAMBLE COMPANY 2021-03-04 US disclosed
WO-2021042127-A1 A PACKAGED HAIR CARE COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2021-03-04 WO disclosed
CN-111658611-A Vaccine delivery system based on microemulsion, and preparation method and application thereof 四川大学 2020-09-15 CN disclosed
EP-3407891-A1 TOPICAL/LOCAL ADMINISTRATION OF INOSITOL HEXAPHOSPHATE AS AN ADJUVANT IN ANTICANCER TREATMENTS LO. LI. Pharma S.r.l. (IT) 2018-12-05 EP disclosed
CN-104887586-B A kind of cosmetic composition for improving skin appearance 上海新高姿化妆品有限公司 2017-12-05 CN disclosed
CN-104739670-B Emulsion stabilizer for low-energy-consumption cosmetic composition and cosmetic composition 广州澳希亚实业有限公司 2017-11-10 CN disclosed
WO-2017130126-A1 TOPICAL/LOCAL ADMINISTRATION OF INOSITOL HEXAPHOSPHATE AS AN ADJUVANT IN ANTICANCER TREATMENTS LO.LI.PHARMA S.R.L. (IT) 2017-08-03 WO disclosed
CN-105411931-A Whitening cosmetic composition SHANGHAI NEW COGI COSMETIC CO LTD 2016-03-23 CN disclosed
US-20080206301-A1 Bone void fillers and methods of making the same KERAPLAST TECHNOLOGIES, LLC 2008-08-28 US disclosed
EP-1919927-A1 USE OF A MINERAL/ORGANIC COMPOSITE MATERIAL IN THE FORM OF AN ULTRAVIOLET RADIATION PROTECTIVE AGENT LVMH RECHERCHE (FR) 2008-05-14 EP disclosed
WO-2007017587-A1 USE OF A MINERAL/ORGANIC COMPOSITE MATERIAL IN THE FORM OF AN ULTRAVIOLET RADIATION PROTECTIVE AGENT LVMH RECHERCHE (FR) 2007-02-15 WO disclosed
EP-1709964-A2 A method of cosmetic depigmentation care by applying at least one aurone ENGELHARD LYON (FR) 2006-10-11 EP disclosed
US-20060153792-A1 Novel cosmetic formulations based on a gel-forming and/or thickening agent and applications of same LUCAS MEYER COSMETICS SARL (FR) 2006-07-13 US disclosed
EP-0887071-B1 Cleansing composition containing a ceramide as stabilizer FD MAN INC (US) 2005-08-31 EP disclosed
EP-1201220-A1 Cosmetic or pharmaceutical compositions containing thermostabilising microcapsules L'OREAL (FR) 2002-05-02 EP disclosed
US-6132750-A Particles of cross-linked proteins and polysaccharides with hydroxamic groups for chelating metals and their uses notably in cosmetics COLETICA (FR) 2000-10-17 US disclosed
EP-0887071-A1 Cleansing composition containing an hydroxy functionalized wax as a stabilizer UNILEVER PLC (GB) 1998-12-30 EP disclosed
US-5302380-A Containing atactic polypropylene; good adhesion REVLON CONSUMER PRODUCTS CORPORATION (US) 1994-04-12 US disclosed