SCHEMBL518985

SCHEMBL518985

O/N=C(\Cl)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
CYP2C19 P33261 2/20 0.43
ALDH1A1 P00352 3/20 0.39
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
TSHR P16473 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
GFER P55789 2/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TRPA1 O75762 1/20 0.37
MAPK1 P28482 1/20 0.37
GSK3B P49841 1/20 0.37
HIF1A Q16665 1/20 0.37
DEPTOR Q8TB45 2/20 0.36
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36
F12 P00748 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL404866 1.00 GAA (0.43) GAACYP2C19ALDH1A1CES2CES1
SCHEMBL404865 1.00 GAA (0.43) GAACYP2C19ALDH1A1CES2CES1
Hydrochloric Acid SCHEMBL5129627 0.97 GAA (0.41) GAACYP2C19ALDH1A1CES2CES1
Hydrochloric Acid SCHEMBL7220016 0.97 GAA (0.41) GAACYP2C19ALDH1A1CES2CES1
Hydrochloric Acid SCHEMBL7220018 0.97 GAA (0.41) GAACYP2C19ALDH1A1CES2CES1
Alcohol SCHEMBL27494925 0.89 ATM (0.43) GAACYP2C19ALDH1A1CES2CES1
Acetic Acid SCHEMBL1849523 0.89 CES2 (0.46) GAACYP2C19ALDH1A1CES2CES1
Acetic Acid SCHEMBL1849527 0.89 CES2 (0.46) GAACYP2C19ALDH1A1CES2CES1
SCHEMBL4045427 0.85 SMN1; SMN2 (0.45) ALDH1A1HPGDSMN1; SMN2GSK3BHIF1A
SCHEMBL4045428 0.85 SMN1; SMN2 (0.45) ALDH1A1HPGDSMN1; SMN2GSK3BHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220202015-A1 STABLE MICROBICIDE COMPOSITION CHEMICREA INC. (JP) 2022-06-30 US claimed
CN-114173563-A Stable microbicide composition 株式会社凯美科瑞亚 2022-03-11 CN claimed
CN-114149378-A Method for preparing polysubstituted p-quinone methylated spiro-framework oxazole 首都医科大学 2022-03-08 CN claimed
WO-2020246452-A1 STABLE MICROBICIDE COMPOSITION 株式会社ケミクレア 2020-12-10 WO claimed
EP-0314422-B1 N-PHENYLALKYLBENZAMIDE FUNGICIDES DOWELANCO (US) 1993-07-28 EP claimed
EP-0314422-A2 N-phenylalkylbenzamide fungicides DOWELANCO (US) 1989-05-03 EP claimed
US-12565492-B2 Anaplastic Lymphoma Kinase (ALK) degraders and uses thereof TRIANA BIOMEDICINES, INC. (US) 2026-03-03 US disclosed
US-20260042752-A1 ANAPLASTIC LYMPHOMA KINASE (ALK) DEGRADERS AND USES THEREOF TRIANA BIOMEDICINES INC (US) 2026-02-12 US disclosed
US-12286439-B2 Inhibitors of ERK nuclear translocation YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-04-29 US disclosed
WO-2025085347-A1 IL4I1 INHIBITORS AND USES THEREOF MERCK SHARP & DOHME LLC (US) 2025-04-24 WO disclosed
CN-115710195-B Trifluoro-olefine compound with nematicidal activity and its preparation method and use 华东理工大学 2025-02-14 CN disclosed
US-20240376089-A1 3-HYDROXY-5-(ISOXAZOL-5-YL) PYRIDINE FORMYLGLYCINE COMPOUNDS, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE CHINA PHARMACEUTICAL UNIVERSITY (CN) 2024-11-14 US disclosed
US-20240246937-A1 IL4I1 INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2024-07-25 US disclosed
EP-0334863-A1 PROCESS FOR THE PREPARATION OF ORGANO N-HYDROXYIMIDATES. ALLIED CORP (US) 1989-10-04 EP disclosed
EP-0314422-A2 N-phenylalkylbenzamide fungicides DOWELANCO (US) 1989-05-03 EP disclosed
WO-1988004291-A1 PROCESS FOR THE PREPARATION OF ORGANO N-HYDROXYIMIDATES ALLIED CORPORATION (US) 1988-06-16 WO disclosed
US-4743701-A Process for the preparation of organo N-hydroxyimidates ALLIED CORPORATION (US) 1988-05-10 US disclosed
CN-85106974-A Ether-derivative herbicides 1987-04-01 CN disclosed
US-4614813-A Process for the preparation of N-hydroxy organo imidate compounds ALLIED CORPORATION (US) 1986-09-30 US disclosed
US-4581365-A Trichloroacryloyl oxime fungicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-04-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042752-A1 ANAPLASTIC LYMPHOMA KINASE (ALK) DEGRADERS AND USES THEREOF ALK, NTRK1, NTRK3 GAA 1685/4885CYP2C19 3231/4885ALDH1A1 2403/4885
US-12286439-B2 Inhibitors of ERK nuclear translocation MAPK1, MAPKAP1, MAPKAPK2 GAA 3589/4885CYP2C19 3302/4885ALDH1A1 2978/4885
US-20240376089-A1 3-HYDROXY-5-(ISOXAZOL-5-YL) PYRIDINE FORMYLGLYCINE COMPOUNDS, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE HIF1AN, HIF1A, EGLN3 GAA 93/4885CYP2C19 519/4885ALDH1A1 1081/4885
US-12565492-B2 Anaplastic Lymphoma Kinase (ALK) degraders and uses thereof ALK, NTRK3, NTRK1 GAA 2291/4885CYP2C19 2064/4885ALDH1A1 2387/4885
US-20240246937-A1 IL4I1 INHIBITORS AND METHODS OF USE IL4I1, IL4, IL2 GAA 3303/4885CYP2C19 423/4885ALDH1A1 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.