Perflubutane

Perflubutane

SCHEMBL5190215

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)F.FC1(F)C(F)(F)C1(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perflubutane SCHEMBL7701005 1.00 LMNA (0.41) LMNAMEN1KMT2ATDP1THRB
Perflenapent SCHEMBL8841157 0.96 LMNA (0.47) LMNAMEN1KMT2ATDP1THRB
Perfluorocyclobutane SCHEMBL8728333 0.91 MEN1 (0.36) LMNAMEN1KMT2ATDP1
Perflunafene SCHEMBL16267616 0.86 MEN1 (0.53) LMNAMEN1KMT2ATDP1THRB
SCHEMBL247546 0.80 LMNA (0.30) LMNA
SCHEMBL7052168 0.80 LMNA (0.30) LMNA
Perfluorocyclobutane SCHEMBL8841181 0.80 MEN1 (0.42) MEN1KMT2ATDP1
SCHEMBL8841150 0.80 MEN1 (0.42) MEN1KMT2ATDP1
Perflubutane SCHEMBL9051673 0.80 LMNA (0.54) LMNATHRBCA2
Perflubutane SCHEMBL111514 0.80 LMNA (0.54) LMNATHRBCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1737998-A2 REMOTE CHAMBER METHODS FOR REMOVING SURFACE DEPOSITS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-01-03 EP disclosed
EP-1733071-A2 REMOTE CHAMBER METHODS FOR REMOVING SURFACE DEPOSITS Massachusetts Institute of Technology (US) 2006-12-20 EP disclosed
EP-1733072-A2 REMOTE CHAMBER METHODS FOR REMOVING SURFACE DEPOSITS Massachusetts Institute Of Technology (US) 2006-12-20 EP disclosed
US-20060144819-A1 Remote chamber methods for removing surface deposits MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2006-07-06 US disclosed
US-20060144820-A1 Remote chamber methods for removing surface deposits MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2006-07-06 US disclosed
WO-2005090638-A9 REMOTE CHAMBER METHODS FOR REMOVING SURFACE DEPOSITS DU PONT (US) 2006-01-26 WO disclosed
US-20050258137-A1 Remote chamber methods for removing surface deposits MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2005-11-24 US disclosed
WO-2005098086-A2 REMOTE CHAMBER METHODS FOR REMOVING SURFACE DEPOSITS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-10-20 WO disclosed
WO-2005095670-A2 REMOTE CHAMBER METHODS FOR REMOVING SURFACE DEPOSITS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-10-13 WO disclosed
WO-2005090638-A2 REMOTE CHAMBER METHODS FOR REMOVING SURFACE DEPOSITS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-09-29 WO disclosed