Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perflubutane SCHEMBL5190215 | 1.00 | LMNA (0.41) | LMNAMEN1KMT2ATDP1THRB | |
| Perflenapent SCHEMBL8841157 | 0.96 | LMNA (0.47) | LMNAMEN1KMT2ATDP1THRB | |
| Perfluorocyclobutane SCHEMBL8728333 | 0.91 | MEN1 (0.36) | LMNAMEN1KMT2ATDP1 | |
| Perflunafene SCHEMBL16267616 | 0.86 | MEN1 (0.53) | LMNAMEN1KMT2ATDP1THRB | |
| SCHEMBL247546 | 0.80 | LMNA (0.30) | LMNA | |
| SCHEMBL7052168 | 0.80 | LMNA (0.30) | LMNA | |
| Perfluorocyclobutane SCHEMBL8841181 | 0.80 | MEN1 (0.42) | MEN1KMT2ATDP1 | |
| SCHEMBL8841150 | 0.80 | MEN1 (0.42) | MEN1KMT2ATDP1 | |
| Perflubutane SCHEMBL9051673 | 0.80 | LMNA (0.54) | LMNATHRBCA2 | |
| Perflubutane SCHEMBL111514 | 0.80 | LMNA (0.54) | LMNATHRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169430-A1 | RESPIRATORY AIDS | Gore Enterprise Holdings, Inc. (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000058437-A1 | RESPIRATORY AIDS | GORE ENTERPRISE HOLDINGS, INC. (US) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000002800-A1 | PROPYLENE POLYMER FOAM FOR THERMAL INSULATION OF CONTAINERS | THE DOW CHEMICAL COMPANY (US) | 2000-01-20 | — | — | WO | disclosed |