Perfluorocyclobutane

Perfluorocyclobutane

SCHEMBL8728333

FC(F)(F)C(F)(F)C(F)(F)F.FC1(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.36

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perflubutane SCHEMBL5190215 0.91 LMNA (0.41) MEN1KMT2ATDP1LMNA
Perflubutane SCHEMBL7701005 0.91 LMNA (0.41) MEN1KMT2ATDP1LMNA
Perflenapent SCHEMBL8841157 0.87 LMNA (0.47) MEN1KMT2ATDP1LMNA
SCHEMBL8841150 0.80 MEN1 (0.42) MEN1KMT2ATDP1
Perfluorocyclobutane SCHEMBL8841181 0.80 MEN1 (0.42) MEN1KMT2ATDP1
Perflutren SCHEMBL34348 0.80 LMNA (0.43) LMNA
Perflutren SCHEMBL1446805 0.80 LMNA (0.43) LMNA
SCHEMBL6236575 0.78
Perflunafene SCHEMBL16267616 0.78 MEN1 (0.53) MEN1KMT2ATDP1LMNA
SCHEMBL7051335 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5733527-A Methods for harmonic imaging with ultrasound ALLIANCE PHARMACEUTICAL CORP. (US) 1998-03-31 US claimed
EP-0730434-A1 HARMONIC ULTRASOUND IMAGING WITH MICROBUBBLES ALLIANCE PHARMACEUTICAL CORPORATION (US) 1996-09-11 EP claimed
WO-1996009793-A1 HARMONIC ULTRASOUND IMAGING WITH MICROBUBBLES ALLIANCE PHARMACEUTICAL CORP. (US) 1996-04-04 WO claimed
US-5605647-A BLEND OF AT LEAST TWO DIFFERENT FLUOROIODOCARBONS AND AT LEAST ONE ADDITIVE SELECTED FROM ALCOHOLS, ESTERS, ETHERS, FLUOROETHERS, HYDROCARBONS, HYDROFLUOROCARBONS, KETONES, PERFLUOROCARBONS IKON CORPORATION (US) 1997-02-25 US disclosed