Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18733433 | 0.85 | TSHR (0.57) | KRASTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL4478554 | 0.84 | ALDH1A1 (0.57) | RAB9ATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3785882 | 0.84 | KDM4E (0.51) | RAB9ATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL1598783 | 0.83 | ALDH1A1 (0.56) | RAB9ATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL10277241 | 0.83 | RAB9A (0.53) | RAB9ATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL20037044 | 0.83 | TDP1 (0.65) | RAB9ATSHRALDH1A1MAPK1TDP1 | |
| SCHEMBL20786953 | 0.83 | KDM4E (0.55) | RAB9ATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL4465081 | 0.82 | MAPT (0.57) | RAB9ATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL1779695 | 0.81 | RAB9A (0.68) | RAB9ATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL411401 | 0.81 | TSPO (0.58) | RAB9ATSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838302-A2 | PEPTIDE DEFORMYLASE INHIBITORS, THEIR USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | The Centre National de la Recherche Scientifique (FR) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077139-A2 | PEPTIDE DEFORMYLASE INHIBITORS, THEIR USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-07-27 | — | — | WO | disclosed |