Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190544 | 0.84 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1KDM4ELMNAKMT2A | |
| SCHEMBL17144543 | 0.78 | SPHK1 (0.48) | MAOBSIGMAR1NPSR1 | |
| SCHEMBL5193550 | 0.78 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1KDM4ELMNAKMT2A | |
| SCHEMBL15303786 | 0.76 | POLB (0.46) | ALDH1A1KDM4EKMT2AMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL9782181 | 0.76 | POLB (0.49) | ALDH1A1L3MBTL1KDM4EKMT2AMAPK1 | |
| SCHEMBL5190692 | 0.76 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KDM4ELMNAKMT2A | |
| SCHEMBL9842333 | 0.76 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1KDM4ELMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9782278 | 0.75 | POLB (0.45) | ALDH1A1KDM4EKMT2AMAPK1MEN1 | |
| SCHEMBL5192506 | 0.75 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KDM4ELMNAMAPK1 | |
| SCHEMBL9595851 | 0.74 | KDM4E (0.52) | ALDH1A1L3MBTL1KDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |