Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190692 | 0.91 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAMAPK1KMT2A | |
| SCHEMBL5192506 | 0.89 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNAMAPK1KDM4E | |
| SCHEMBL5190175 | 0.87 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1LMNAKMT2AKDM4E | |
| SCHEMBL5190296 | 0.86 | SIGMAR1 (0.44) | ALDH1A1L3MBTL1KDM4ESIGMAR1 | |
| SCHEMBL5192022 | 0.84 | KMT2A (0.48) | ALDH1A1KMT2AKDM4EPOLB | |
| SCHEMBL5190638 | 0.84 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1LMNAMAPK1KMT2A | |
| SCHEMBL5193050 | 0.82 | KMT2A (0.41) | ALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL9842333 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNAMAPK1KMT2A | |
| SCHEMBL5191954 | 0.79 | KMT2A (0.44) | ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL22639906 | 0.75 | TDP1 (0.57) | ALDH1A1L3MBTL1LMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | disclosed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | disclosed |