Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183354 | 0.78 | KDM4E (0.33) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL7935896 | 0.78 | CRHBP (0.38) | KDM4EMEN1ALDH1A1LMNATP53 | |
| SCHEMBL5181213 | 0.75 | KDM4E (0.32) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL7772861 | 0.75 | CCR1 (0.56) | KDM4EALDH1A1LMNATP53HPGD | |
| SCHEMBL11002658 | 0.75 | PLAU (0.38) | KDM4EALDH1A1LMNATP53HSP90AA1 | |
| SCHEMBL557084 | 0.74 | CCR1 (0.43) | KDM4ELMNATP53HSP90AA1ALOX15 | |
| SCHEMBL29533844 | 0.74 | CCR1 (0.43) | KDM4ELMNATP53HSP90AA1ALOX15 | |
| SCHEMBL1391531 | 0.73 | — | — | |
| SCHEMBL31215731 | 0.72 | MEN1 (0.35) | KDM4EMEN1USP2ALDH1A1LMNA | |
| SCHEMBL113907 | 0.69 | LMNA (0.58) | KDM4EMEN1USP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1563852-B1 | COMPOUNDS WHICH CAN BE USED TO DIAGNOSE AND MONITOR DISEASES ASSOCIATED WITH THE FORMATION OF AMYLOID PROTEIN FIBRILS | CETIR CT MEDIC S A (ES) | 2007-11-21 | — | — | EP | claimed |