Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5194807 | 0.79 | MAPK1 (0.60) | HSD17B3BRPF1ALOX15BRD4CREBBP | |
| SCHEMBL2824864 | 0.78 | BRD4 (0.56) | HSD17B3ALOX15BRD4CREBBPHTT | |
| SCHEMBL5191836 | 0.77 | ITGB3 (0.52) | HSD17B3BRPF1ALOX15HSD17B10BRD4 | |
| SCHEMBL5473498 | 0.75 | HSD17B3 (0.42) | HSD17B3BRPF1ALOX15HSD17B10BRD4 | |
| SCHEMBL5194517 | 0.75 | KDM4E (0.56) | HSD17B3BRPF1ALOX15HSD17B10BRD4 | |
| SCHEMBL5193362 | 0.75 | BRD4 (0.61) | HSD17B3BRPF1ALOX15HSD17B10BRD4 | |
| SCHEMBL5193610 | 0.72 | BRPF1 (0.44) | HSD17B3BRPF1ALOX15HSD17B10BRD4 | |
| SCHEMBL5193417 | 0.72 | GSK3A (0.51) | BRPF1BRD4MAPK1GSK3AGSK3B | |
| SCHEMBL5470380 | 0.72 | BRPF1 (0.41) | HSD17B3BRPF1ALOX15HSD17B10BRD4 | |
| SCHEMBL27993916 | 0.71 | MAPK1 (0.48) | HSD17B3ALOX15HSD17B10BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1813603-A1 | AROMATIC AMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICAL USES OF BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232594-A1 | Aromatic amide derivatives, medicinal compositions containing the same, medical uses of both | AVPR2, AVPR1A, AVPR1B | HSD17B3 704/4885BRPF1 4136/4885ALOX15 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.