Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193825 | 0.78 | HSD17B3 (0.50) | BRD4CREBBPALOX15HSD17B3HTT | |
| SCHEMBL17506418 | 0.76 | AHR (0.50) | BRD4CREBBPAHRPDK2HTT | |
| SCHEMBL28355036 | 0.76 | BRD4 (0.61) | BRD4CREBBPALOX15AHRPDK2 | |
| SCHEMBL30937679 | 0.75 | BRD4 (0.51) | BRD4CREBBPALOX15AHRPDK2 | |
| SCHEMBL9202802 | 0.75 | ALOX15 (0.53) | BRD4CREBBPALOX15 | |
| SCHEMBL23119793 | 0.73 | MAPT (0.58) | BRD4CREBBPAHRPDK2NPC1 | |
| SCHEMBL677636 | 0.72 | BRD4 (1.00) | BRD4CREBBPAHRPDK2NPC1 | |
| SCHEMBL7083744 | 0.72 | BRD4 (0.61) | BRD4CREBBPALOX15AHRPDK2 | |
| SCHEMBL13947064 | 0.72 | BRD4 (0.61) | BRD4CREBBPALOX15AHRPDK2 | |
| SCHEMBL9198302 | 0.72 | ALOX15 (0.50) | BRD4CREBBPALOX15ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146988-B1 | NEW 4,8-DIPHENYL-POLYAZANAPHTHALENE DERIVATIVES | ALMIRALL SA (ES) | 2012-08-15 | — | — | EP | disclosed |
| EP-2196465-A1 | (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2010-06-16 | — | — | EP | disclosed |