Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195352 | 0.86 | ALDH1A1 (0.58) | KDM4EALDH1A1CA1CA2POLB | |
| SCHEMBL11475368 | 0.84 | EPHX2 (0.67) | KDM4EALDH1A1CA1CA2MTNR1A | |
| SCHEMBL5191195 | 0.83 | MEN1 (0.59) | KDM4EALDH1A1CA1CA2 | |
| SCHEMBL5213635 | 0.79 | KDM4E (0.53) | KDM4EALDH1A1CA1CA2MTNR1A | |
| SCHEMBL11654998 | 0.78 | CA1 (0.77) | ALDH1A1CA1CA2MTNR1AMTNR1B | |
| SCHEMBL5195710 | 0.78 | ALDH1A1 (0.58) | ALDH1A1CA1CA2RAB9APOLB | |
| SCHEMBL29557686 | 0.77 | POLB (0.60) | ALDH1A1POLB | |
| SCHEMBL3347513 | 0.77 | POLB (0.60) | ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL11659562 | 0.77 | CA1 (0.76) | ALDH1A1CA1CA2MTNR1AMTNR1B | |
| SCHEMBL30475090 | 0.76 | POLB (0.59) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968206-B8 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX INC (US) | 2007-01-24 | — | — | EP | claimed |
| EP-0968206-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2000-01-05 | — | — | EP | claimed |
| WO-1998037079-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1998-08-27 | — | — | WO | claimed |