Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455690 | 0.89 | LMNA (0.55) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL5697445 | 0.82 | AR (0.60) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL4441997 | 0.82 | LMNA (0.55) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL4807382 | 0.81 | LMNA (0.59) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL6439469 | 0.81 | LMNA (0.59) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL11567748 | 0.80 | LMNA (0.58) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10891579 | 0.80 | LMNA (0.65) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10414255 | 0.79 | LMNA (0.61) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL10599073 | 0.79 | LMNA (0.61) | LMNAMAPTCYP19A1CYP3A4KMT2A | |
| SCHEMBL11408474 | 0.79 | LMNA (0.61) | LMNAMAPTCYP19A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658083-B1 | ENHANCEMENT OF ACTIVITY AND/OR DURATION OF ACTION OF SELECTED ANTI-INFLAMMATORY STEROIDS | BODOR NICHOLAS S (US) | 2007-08-08 | — | — | EP | disclosed |
| EP-1658083-A1 | ENHANCEMENT OF ACTIVITY AND/OR DURATION OF ACTION OF SELECTED ANTI-INFLAMMATORY STEROIDS | BODOR, Nicholas S. (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2004112800-A1 | ENHANCEMENT OF ACTIVITY AND/OR DURATION OF ACTION OF SELECTED ANTI-INFLAMMATORY STEROIDS | BODOR NICHOLAS S (US) | 2004-12-29 | — | — | WO | disclosed |
| EP-0334853-A4 | SOFT STEROIDS HAVING ANTI-INFLAMMATORY ACTIVITY. | BODOR NICHOLAS S | 1990-02-26 | — | — | EP | disclosed |
| WO-1989003390-A1 | SOFT STEROIDS HAVING ANTI-INFLAMMATORY ACTIVITY | BODOR NICHOLAS S (US) | 1989-04-20 | — | — | WO | disclosed |