SCHEMBL4441997

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6439469	0.87	LMNA (0.59)	LMNAMAPTCYP19A1NR3C1PGR
	SCHEMBL4455690	0.86	LMNA (0.55)	LMNAMAPTCYP19A1NR3C1PGR
	SCHEMBL4807382	0.84	LMNA (0.59)	LMNAMAPTCYP19A1NR3C1PGR
	SCHEMBL4444218	0.83	AR (0.61)	LMNAMAPTNR3C1PGRCYP3A4
	SCHEMBL5195019	0.82	LMNA (0.59)	LMNAMAPTCYP19A1NR3C1PGR
	SCHEMBL3679824	0.78	NR3C1 (0.64)	LMNANR3C1PGRCYP3A4ABCC3
	SCHEMBL6447018	0.77	LMNA (0.65)	LMNAMAPTCYP19A1NR3C1PGR
	SCHEMBL6449571	0.77	LMNA (0.65)	LMNAMAPTCYP19A1NR3C1PGR
	SCHEMBL11817969	0.77	LMNA (0.62)	LMNAMAPTCYP19A1PGRCYP3A4
	SCHEMBL4210068	0.76	LMNA (0.59)	LMNAMAPTCYP19A1NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.