SCHEMBL4455690

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5195019	0.89	LMNA (0.59)	LMNAMAPTPGRNR3C1CYP3A4
	SCHEMBL6439469	0.89	LMNA (0.59)	LMNAMAPTPGRNR3C1ABCC3
	SCHEMBL4441997	0.86	LMNA (0.55)	LMNAMAPTPGRNR3C1ABCC3
	SCHEMBL4443905	0.83	AR (0.59)	LMNAMAPTPGRNR3C1NR1I2
	SCHEMBL4807382	0.82	LMNA (0.59)	LMNAMAPTPGRNR3C1NR1I2
	SCHEMBL9501753	0.78	LMNA (0.61)	LMNAMAPTPGRCYP3A4HIF1A
	SCHEMBL11822457	0.78	LMNA (0.58)	LMNAMAPTPGRNR3C1ABCC3
	SCHEMBL6449571	0.77	LMNA (0.65)	LMNAMAPTPGRNR3C1ABCB11
	SCHEMBL6447018	0.77	LMNA (0.65)	LMNAMAPTPGRNR3C1ABCB11
	SCHEMBL1685726	0.77	KMT2A (0.60)	LMNAMAPTPGRNR3C1ABCC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.