Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195026 | 1.00 | ITGA4 (0.43) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6166829 | 0.99 | ITGA4 (0.43) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6166820 | 0.99 | ITGA4 (0.43) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6166830 | 0.99 | ITGA4 (0.43) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6166824 | 0.94 | ITGA4 (0.39) | ITGA4ITGB1 | |
| SCHEMBL6166470 | 0.92 | ITGA4 (0.44) | ITGA4ITGB1 | |
| SCHEMBL6166460 | 0.92 | ITGA4 (0.44) | ITGA4ITGB1 | |
| SCHEMBL6164563 | 0.91 | ITGB1 (0.46) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6164569 | 0.91 | ITGB1 (0.46) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6515553 | 0.91 | ITGA4 (0.45) | ITGA4ITGB1ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381595-B1 | BIS(TRIFLUOROMETHYL)HYDANTOINS AS INTERMEDIATES FOR PHARMACEUTICALLY ACTIVE INGREDIENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1373249-B1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTIINFLAMATORY AGENT | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6794517-B2 | AS CHEMICAL INTERMEDIATE TO FORM DRUGS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-09-21 | — | — | US | disclosed |
| EP-1381595-A1 | BIS(TRIFLUOROMETHYL)HYDANTOINS AS INTERMEDIATES FOR PHARMACEUTICALLY ACTIVE INGREDIENTS | Aventis Pharma Deutschland GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| US-6680333-B2 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; ANTIALLERGENS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-01-20 | — | — | US | disclosed |
| EP-1373249-A1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTINFLAMATORY AGENT | Aventis Pharma Deutschland GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| US-20030073723-A1 | Novel imidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-04-17 | — | — | US | disclosed |
| US-20020183374-A1 | Bis(trifluoromethyl)hydantoins as intermediates for pharmaceutically active ingredients | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2002-12-05 | — | — | US | disclosed |
| WO-2002072573-A1 | IMIDAZOLIDINE DERIVATIVES, THEIR PREPARATION, AND THEIR USE AS ANTINFLAMATORY AGENT. | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-09-19 | — | — | WO | disclosed |
| WO-2002072557-A1 | BIS(TRIFLUOROMETHYL)HYDANTOINS AS INTERMEDIATES FOR PHARMACEUTICALLY ACTIVE INGREDIENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073723-A1 | Novel imidazolidine derivatives, their preparation, their use and pharmaceutical preparations comprising them | VCAM1, ITGA4, ITGA1 | ITGA4 2/4885ITGB1 10/4885ITGB7 18/4885 |
| US-20020183374-A1 | Bis(trifluoromethyl)hydantoins as intermediates for pharmaceutically active ingredients | HRH1, ALDH7A1, HRH4 | ITGA4 4753/4885ITGB1 4637/4885ITGB7 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.