SCHEMBL5195259

SCHEMBL5195259

CCc1cc(CC)c(O)c(OC(=O)O)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.42
HSPA5 P11021 1/20 0.39
PTGS2 P35354 2/20 0.37
AKT1 P31749 1/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
POLB P06746 1/20 0.35
POLA1 P09884 1/20 0.35
ANTXR2 P58335 1/20 0.35
ALOX5 P09917 3/20 0.35
NFKB1 P19838 2/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
GAA P10253 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PTGS1 P23219 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5676409 0.90 PTPN1 (0.39) TRPV1HSPA5PTGS2AKT1ALOX5
SCHEMBL5680771 0.88 TRPV1 (0.42) TRPV1AKT1POLBALOX5NFKB1
SCHEMBL5678278 0.88 ALOX5 (0.43) TRPV1PTGS2ALOX5NFKB1NFKB2
SCHEMBL5677035 0.86 ALOX5 (0.49) TRPV1PTGS2ALOX5TSHR
SCHEMBL5678365 0.85 TRPV1 (0.46) TRPV1PTGS2ALOX5NFKB1NFKB2
SCHEMBL5193770 0.84 TRPV1 (0.48) TRPV1PTGS2ALOX5ALDH1A1
SCHEMBL5680795 0.84 HMGB1 (0.42) PTGS2RXRARXRBPOLBPOLA1
SCHEMBL5680643 0.82 KDM4E (0.36) TRPV1HSPA5PTGS2POLBALOX5
SCHEMBL5586993 0.81 PTPN1 (0.42) TRPV1PTGS2ALOX5NFKB1NFKB2
SCHEMBL981615 0.79 ALOX5 (0.44) TRPV1PTGS2ALOX5NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620447-B1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEM PATENTS INC (US) 2007-08-08 EP disclosed
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III ZHAO BAIYI 2006-02-16 US disclosed
EP-1620447-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III Exxonmobil Chemical Patents Inc. (US) 2006-02-01 EP disclosed
WO-2003102006-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III COMT, CD69, SPR TRPV1 1255/4885HSPA5 2342/4885PTGS2 1827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.