SCHEMBL5676409

SCHEMBL5676409

CCCc1cc(CC)cc(OC(=O)O)c1O

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.39
PTPN11 Q06124 3/20 0.39
PTPN2 P17706 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
ALOX5 P09917 6/20 0.37
DHFR P00374 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
HMGCR P04035 1/20 0.37
AKT1 P31749 1/20 0.36
PTGS2 P35354 4/20 0.35
PTGS1 P23219 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
HSPA5 P11021 1/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
PRKCI P41743 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5586993 0.92 PTPN1 (0.42) PTPN1PTPN11PTPN2TRPV1ALOX5
SCHEMBL5678278 0.91 ALOX5 (0.43) PTPN1TRPV1ALOX5NFKB1NFKB2
SCHEMBL5195259 0.90 TRPV1 (0.42) TRPV1ALOX5DHFRNFKB1NFKB2
SCHEMBL5677035 0.90 ALOX5 (0.49) PTPN1TRPV1ALOX5PTGS2PPARG
SCHEMBL5680771 0.89 TRPV1 (0.42) PTPN1PTPN11PTPN2TRPV1ALOX5
SCHEMBL5676247 0.88 ALOX5 (0.40) PTPN1PTPN11TRPV1ALOX5NFKB1
SCHEMBL5678371 0.87 ALOX5 (0.46) TRPV1ALOX5PTGS2PPARGPPARA
SCHEMBL5676110 0.85 ALOX5 (0.43) PTPN1PTPN11TRPV1ALOX5NFKB1
SCHEMBL5676230 0.84 ALOX5 (0.49) TRPV1ALOX5PTGS2PPARGPPARA
SCHEMBL5678365 0.83 TRPV1 (0.46) TRPV1ALOX5NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III ZHAO BAIYI 2006-02-16 US disclosed
EP-1620447-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III Exxonmobil Chemical Patents Inc. (US) 2006-02-01 EP disclosed
WO-2003102006-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III COMT, CD69, SPR PTPN1 4673/4885PTPN11 4670/4885PTPN2 4744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.