SCHEMBL5195489

SCHEMBL5195489

CCCc1ccc(OC(=O)O)c(O)c1C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.41
ELANE P08246 1/20 0.35
METAP2 P50579 1/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTPN1 P18031 3/20 0.35
PTPN11 Q06124 2/20 0.35
TYR P14679 1/20 0.35
HMGCR P04035 1/20 0.34
PTPN2 P17706 1/20 0.34
ALOX5 P09917 1/20 0.34
FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5590531 0.91 TYR (0.43) ELANEMETAP2TSHRTYRALOX5
SCHEMBL5678190 0.89 TYR (0.49) MEN1MAPTTSHRKMT2ATYR
SCHEMBL5587866 0.88 GABRA1 (0.36) MAPTKMT2AHSD17B10FFAR4
SCHEMBL1837933 0.87 FFAR4 (0.39) PRKCIMETAP2KMT2AHSD17B10FFAR4
SCHEMBL5590560 0.86 MAPT (0.32) MAPTFFAR4
SCHEMBL5588622 0.84 PRKCI (0.41) PRKCIMEN1CYP1A2MAPTTSHR
SCHEMBL5676413 0.83 PRKCI (0.39) PRKCIMEN1CYP1A2MAPTTSHR
SCHEMBL5680760 0.83 PRKCI (0.41) PRKCIELANEMEN1CYP1A2MAPT
SCHEMBL5676396 0.82 ALOX5 (0.41) PRKCITSHRTYRALOX5
SCHEMBL5590637 0.82 TYR (0.35) TSHRTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620447-B1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEM PATENTS INC (US) 2007-08-08 EP disclosed
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III ZHAO BAIYI 2006-02-16 US disclosed
EP-1620447-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III Exxonmobil Chemical Patents Inc. (US) 2006-02-01 EP disclosed
WO-2003102006-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III COMT, CD69, SPR PRKCI 4096/4885ELANE 2735/4885METAP2 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.