Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | SCD | O00767 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196774 | 0.84 | NPC1 (0.56) | LMNANPC1RAB9AMAPTPOLB | |
| SCHEMBL5196570 | 0.83 | MAPT (0.45) | NPC1RAB9AMAPTPOLBNPSR1 | |
| SCHEMBL5196996 | 0.81 | ADORA3 (0.51) | NPC1RAB9AMAPTKDM4EADORA3 | |
| SCHEMBL13685249 | 0.72 | SMN1; SMN2 (0.61) | LMNANPC1RAB9AMAPTKDM4E | |
| SCHEMBL5193555 | 0.71 | KMT2A (0.55) | LMNAMAPTKDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL2753357 | 0.71 | KDR (0.77) | LMNANPC1RAB9AMAPTPOLB | |
| SCHEMBL2753581 | 0.71 | ADORA2A (0.61) | LMNANPC1RAB9AMAPTPOLB | |
| SCHEMBL16774973 | 0.70 | MAPT (0.77) | LMNANPC1RAB9AMAPTKDM4E | |
| SCHEMBL12963175 | 0.70 | MAPT (0.75) | LMNANPC1RAB9AMAPTPOLB | |
| SCHEMBL2754003 | 0.69 | SCD (0.69) | LMNANPC1RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321463-B1 | Thiazole derivatives and their use for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC (CA) | 2007-08-08 | — | — | EP | claimed |