Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195752 | 0.84 | ALDH1A1 (0.48) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL5194973 | 0.83 | KMT2A (0.57) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL3811715 | 0.75 | NPSR1 (0.69) | KMT2AMEN1KDM4ELMNANPSR1 | |
| SCHEMBL5196570 | 0.73 | MAPT (0.45) | KMT2AMAPTNPSR1RXFP1ALDH1A1 | |
| SCHEMBL13685249 | 0.72 | SMN1; SMN2 (0.61) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL634004 | 0.72 | MEN1 (0.75) | KMT2AMEN1KDM4ELMNAMAPT | |
| Biphenyl SCHEMBL9176116 | 0.69 | LMNA (0.64) | KMT2AMEN1KDM4ELMNAALDH1A1 | |
| SCHEMBL5196996 | 0.68 | ADORA3 (0.51) | KMT2AMEN1KDM4EMAPTRXFP1 | |
| SCHEMBL5196161 | 0.68 | RAB9A (0.46) | KMT2AMEN1KDM4ELMNAMAPT | |
| SCHEMBL5194094 | 0.68 | ALDH1A1 (0.53) | KMT2AMEN1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321463-B1 | Thiazole derivatives and their use for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC (CA) | 2007-08-08 | — | — | EP | claimed |