Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195844 | 0.84 | DHODH (0.49) | KDM4ENPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL5195674 | 0.81 | XDH (0.62) | ADORA3XDHADORA1ADORA2ATMIGD3 | |
| SCHEMBL5196804 | 0.81 | LMNA (0.53) | ADORA3ADORA1ADORA2AKDM4ENPC1 | |
| SCHEMBL5196570 | 0.78 | MAPT (0.45) | ADORA3ADORA1ADORA2ANPC1RAB9A | |
| SCHEMBL5196165 | 0.75 | MAPT (0.45) | ADORA3XDHKDM4ENPC1RAB9A | |
| SCHEMBL3817368 | 0.75 | HPGD (0.56) | ADORA3KDM4ENPC1RAB9AMAPT | |
| SCHEMBL14874759 | 0.72 | SMN1; SMN2 (0.64) | XDHKDM4ENPC1RAB9AMAPT | |
| SCHEMBL13685249 | 0.70 | SMN1; SMN2 (0.61) | KDM4ENPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL1082315 | 0.70 | KDM4E (0.62) | KDM4ENPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL2817297 | 0.70 | KDM4E (0.65) | KDM4ENPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321463-B1 | Thiazole derivatives and their use for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC (CA) | 2007-08-08 | — | — | EP | claimed |