SCHEMBL5196886

SCHEMBL5196886

CCSc1cncc(C(C)=CCCN)c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.34
TBXAS1 P24557 2/20 0.32
GAA P10253 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8590780 0.77 KDM4E (0.44) TBXAS1
SCHEMBL8018174 0.76 GAA (0.30) GAARAB9A
SCHEMBL5406058 0.74 MKNK2 (0.38) TBXAS1
SCHEMBL7738084 0.73 TBXAS1 (0.38) TBXAS1
SCHEMBL18485279 0.72 SIRT2 (0.50) AOC3GAARAB9A
SCHEMBL6818202 0.70 HCAR2 (0.52) GAARAB9A
SCHEMBL3128200 0.68 TBXAS1 (0.61) TBXAS1GAA
SCHEMBL7071004 0.66 TBXAS1 (0.35) TBXAS1GAA
SCHEMBL24233673 0.64 KDM4E (0.47) TBXAS1
Nitric Acid SCHEMBL5741778 0.64 CYP2C9 (0.44) GAARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1814853-A2 HYDROXYBENZOATE SALTS OF METANICOTINE COMPOUNDS Targacept, Inc. (US) 2007-08-08 EP disclosed
WO-2006053039-A2 HYDROXYBENZOATE SALTS OF METANICOTINE COMPOUNDS TARGACEPT, INC. (US) 2006-05-18 WO disclosed