Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5586386 | 0.81 | ALDH1A1 (0.39) | FDPSALDH1A1LMNAHSD17B10 | |
| SCHEMBL393486 | 0.78 | CHRM1 (0.34) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL201294 | 0.78 | CHRM1 (0.34) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL28206327 | 0.74 | CA2 (0.43) | CA2MAPK1 | |
| SCHEMBL28084857 | 0.71 | CA2 (0.45) | CA2MAPK1 | |
| SCHEMBL671801 | 0.71 | LMNA (0.37) | ADRA1ATDP1FDPSLMNAHSD17B10 | |
| SCHEMBL27558141 | 0.71 | TDP1 (0.47) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL29134691 | 0.70 | TSHR (0.36) | CHRM1ADRA1AAKR1A1CHRM3HTR2A | |
| SCHEMBL2823350 | 0.69 | ALDH1A1 (0.44) | TDP1FDPSALDH1A1LMNAHSD17B10 | |
| SCHEMBL9718417 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611192-A4 | JOINT FILL COMPOSITION AND METHOD | BAYSYSTEMS NORTH AMERICA LLC (US) | 2007-12-05 | — | — | EP | disclosed |
| EP-1611192-A2 | JOINT FILL COMPOSITION AND METHOD | Polythane Systems, Inc. (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004081438-A3 | JOINT FILL COMPOSITION AND METHOD | POLYTHANE SYSTEMS INC (US) | 2004-11-11 | — | — | WO | disclosed |
| WO-2004081438-A2 | JOINT FILL COMPOSITION AND METHOD | POLYTHANE SYSTEMS, INC. (US) | 2004-09-23 | — | — | WO | disclosed |