Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674538 | 0.84 | TAAR1 (0.48) | LMNARAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL8712652 | 0.80 | MAOB (0.48) | MAPTLMNAKMT2AALDH1A1MAPK1 | |
| SCHEMBL10396333 | 0.79 | RAB9A (0.62) | MAPTLMNARAB9AMEN1KMT2A | |
| Benzophenone SCHEMBL28231198 | 0.78 | RAB9A (0.78) | MAPTLMNARAB9AMEN1KMT2A | |
| SCHEMBL29143580 | 0.78 | RAB9A (0.78) | MAPTLMNARAB9AMEN1KMT2A | |
| SCHEMBL41657 | 0.78 | RAB9A (0.78) | MAPTLMNARAB9AMEN1KMT2A | |
| Benzene SCHEMBL28384085 | 0.78 | RAB9A (0.78) | MAPTLMNARAB9AMEN1KMT2A | |
| SCHEMBL13534566 | 0.78 | RAB9A (0.78) | MAPTLMNARAB9AMEN1KMT2A | |
| SCHEMBL28246134 | 0.78 | RAB9A (0.78) | MAPTLMNARAB9AMEN1KMT2A | |
| Benzophenone SCHEMBL15567912 | 0.78 | RAB9A (0.78) | MAPTLMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844042-A1 | INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006076529-A1 | INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. (US) | 2006-07-20 | — | — | WO | disclosed |