Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864615 | 0.86 | ACHE (0.51) | ACHESLC6A4UTS2R | |
| SCHEMBL5197871 | 0.85 | NPSR1 (0.48) | NPSR1SMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL3868777 | 0.82 | ACHE (0.67) | NPSR1ACHESLC6A4SMN1; SMN2HSD17B10 | |
| SCHEMBL3874629 | 0.80 | SLC6A4 (0.45) | ACHESLC6A4UTS2R | |
| SCHEMBL3870423 | 0.79 | NPSR1 (0.60) | NPSR1ACHESLC6A4SMN1; SMN2HSD17B10 | |
| SCHEMBL9713689 | 0.76 | NPSR1 (1.00) | NPSR1SMN1; SMN2HSD17B10ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL3869736 | 0.72 | ACHE (0.59) | NPSR1ACHESLC6A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL3863029 | 0.70 | ACHE (0.71) | NPSR1ACHESLC6A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL3870426 | 0.69 | NPSR1 (0.48) | NPSR1SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3867616 | 0.69 | ACHE (0.70) | NPSR1ACHESLC6A4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362844-B1 | BENZYLAMINE ANALOGUE | BTG INT LTD (GB) | 2007-12-05 | — | — | EP | disclosed |