Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197867 | 0.85 | NPSR1 (0.57) | NPSR1KMT2ATDP1MEN1LMNA | |
| SCHEMBL3870426 | 0.81 | NPSR1 (0.48) | NPSR1KMT2ATDP1MEN1LMNA | |
| SCHEMBL5199102 | 0.77 | CYP1A2 (0.40) | TDP1CYP1A2FAAHSMN1; SMN2 | |
| SCHEMBL3864608 | 0.72 | SMN1; SMN2 (0.47) | NPSR1KMT2ATDP1MEN1LMNA | |
| SCHEMBL3864615 | 0.72 | ACHE (0.51) | RAB9A | |
| Hydrochloric Acid SCHEMBL3868777 | 0.72 | ACHE (0.67) | NPSR1KMT2ATDP1MEN1LMNA | |
| SCHEMBL3870423 | 0.69 | NPSR1 (0.60) | NPSR1KMT2ATDP1MEN1LMNA | |
| SCHEMBL9713689 | 0.68 | NPSR1 (1.00) | NPSR1KMT2ATDP1MEN1LMNA | |
| SCHEMBL3874629 | 0.68 | SLC6A4 (0.45) | FAAH | |
| SCHEMBL3870674 | 0.68 | ACHE (0.44) | TDP1CYP1A2FAAHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362844-B1 | BENZYLAMINE ANALOGUE | BTG INT LTD (GB) | 2007-12-05 | — | — | EP | disclosed |