SCHEMBL5198307

SCHEMBL5198307

CCc1c(C)nc2nc(C)nn2c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.47
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
MAPT P10636 2/20 0.37
DPP4 P27487 1/20 0.37
GAA P10253 1/20 0.36
THRB P10828 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
SLC16A3 O15427 1/20 0.35
HTT P42858 1/20 0.35
KDM5B Q9UGL1 1/20 0.35
TP53 P04637 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 3/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24572157 0.81 KDM4E (0.58) NPSR1KDM4EMEN1KMT2AMAPT
SCHEMBL5197330 0.74 MEN1 (0.55) MEN1KMT2AMAPTGAASMN1; SMN2
SCHEMBL5706381 0.73 KDM4E (0.39) NPSR1KDM4EMEN1KMT2AMAPT
SCHEMBL21565452 0.68 NPSR1 (0.49) NPSR1KDM4EMEN1KMT2AMAPT
SCHEMBL17351817 0.67 KDM4E (0.33) NPSR1KDM4EMEN1KMT2AMAPT
SCHEMBL5104023 0.67 KDM4E (0.31) NPSR1KDM4E
SCHEMBL14013824 0.67 PRKAB2 (0.39) KDM4EMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL19194488 0.67 TP53 (0.40) NPSR1KDM4EMAPTGAASMN1; SMN2
SCHEMBL8004653 0.66 KDM4E (0.36) NPSR1KDM4EMAPTSMN1; SMN2ALDH1A1
SCHEMBL12806621 0.66 KDM4E (0.33) KDM4EGAASMN1; SMN2HTTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP claimed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US claimed
US-4078937-A SULFUR, HYDROXYTETRAAZAINDENE FUJI PHOTO FILM CO., LTD. (JA) 1978-03-14 US claimed
EP-1217432-B1 Silver halide photographic light-sensitive material and method for processing the same FUJIFILM CORP (JP) 2007-08-15 EP disclosed
EP-1109060-B1 Silver halide photographic element EASTMAN KODAK CO (US) 2003-06-04 EP disclosed
US-6544718-B2 Hydrophilic colloid layer includes a disulfide or dimercapto compound of given formula; for photomechanical plate-making that exhibits ultrahigh-contrast photographic characteristics FUJI PHOTO FILM CO., LTD. (JP) 2003-04-08 US disclosed
US-20030022113-A1 Silver halide photographic light-sensitive material and method for processing same FUJI PHOTO FILM CO., LTD. 2003-01-30 US disclosed
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP disclosed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US disclosed
EP-1217432-A2 Silver halide photographic light-sensitive material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 2002-06-26 EP disclosed
EP-0843209-B1 Silver halide emulsion manufacturing method EASTMAN KODAK CO (US) 2001-09-05 EP disclosed
US-4863843-A AROMATIC DIOL, SULFONATE MITSUBISHI PAPER MILLS, LTD. (JP) 1989-09-05 US disclosed
EP-0312959-A1 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1989-04-26 EP disclosed
EP-0122125-B1 SILVER HALIDE EMULSION KONICA CORPORATION (JP) 1987-07-15 EP disclosed
EP-0175366-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-03-26 EP disclosed
US-4565778-A COMPRISING CORE/SHELL GRAINS OF SILVER IODOBROMIDE REPENED BY A LABILE SELENIUM COMPOUND;PHOTOSENSITIVITY;ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-01-21 US disclosed
US-4542094-A HYDROXYTETRAZAINDENES AND MERCAPTO-NITROGENCONTAINING HETEROCYLIC COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-17 US disclosed
EP-0122125-A1 Silver halide emulsion KONICA CORPORATION (JP) 1984-10-17 EP disclosed
EP-0121435-A1 Silver halide photographic materials KONICA CORPORATION (JP) 1984-10-10 EP disclosed
EP-0107488-A2 Silver halide emulsions KONICA CORPORATION (JP) 1984-05-02 EP disclosed