SCHEMBL5706381

SCHEMBL5706381

Cc1nc2nc(C)c(S)c(O)n2n1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.31
GAA P10253 1/20 0.30
THRB P10828 1/20 0.30
TP53 P04637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21565452 0.71 NPSR1 (0.49) KDM4ENPSR1MEN1KMT2APOLB
SCHEMBL9564930 0.64 KDM4E (0.40) KDM4ENPSR1MEN1KMT2APOLB
SCHEMBL23568229 0.63
SCHEMBL9505954 0.63 KDM4E (0.35) KDM4ENPSR1MEN1KMT2APOLB
SCHEMBL11930694 0.63 KDM4E (0.38) KDM4ENPSR1MEN1KMT2APOLB
SCHEMBL19939409 0.61 KDM4E (0.35) KDM4ENPSR1POLBGAATP53
SCHEMBL9504134 0.61 TP53 (0.36) KDM4ENPSR1POLBGAATP53
SCHEMBL4613719 0.61 L3MBTL1 (0.46) GAATP53L3MBTL1
SCHEMBL6261617 0.61 ALDH1A1 (0.45) GAATP53L3MBTL1
SCHEMBL19194916 0.60 KDM4E (0.36) KDM4ENPSR1KMT2APOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0233396-B1 SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (4) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-07-31 EP claimed
US-4724200-A CRYSTAL STRUCTURE EASTMAN KODAK COMPANY (US) 1988-02-09 US claimed
EP-0961165-B1 Direct x-ray elements capable of handling in ambient light EASTMAN KODAK CO (US) 2006-11-02 EP disclosed
EP-0881536-B1 Dual-coated radiographic elements with limited hydrophilic colloid coating coverages EASTMAN KODAK CO (US) 2005-11-02 EP disclosed
EP-1054295-B1 Developing/fixing monobath and its use for processing low silver black-and-white photographic elements EASTMAN KODAK CO (US) 2005-08-03 EP disclosed
EP-0930533-B1 Direct dental x-ray films adapted for room light handling EASTMAN KODAK CO (US) 2004-03-17 EP disclosed
EP-1054294-B1 Two-stage processing of low silver black-and-white photographic elements EASTMAN KODAK CO (US) 2002-09-25 EP disclosed
US-6291153-B1 X-RAY FILM WITH SILVER HALIDE EMULSION HAVING BROMIDE WITH SOME IODIDE EASTMAN KODAK COMPANY 2001-09-18 US disclosed
EP-1054292-A1 Low silver halide radiographic elements for enhanced wet processing EASTMAN KODAK COMPANY (US) 2000-11-22 EP disclosed
EP-1054294-A1 Two-stage processing of low silver black-and-white photographic elements EASTMAN KODAK COMPANY (US) 2000-11-22 EP disclosed
EP-1054295-A1 Developing/fixing monobath and its use for processing low silver black-and-white photographic elements EASTMAN KODAK COMPANY (US) 2000-11-22 EP disclosed
US-5372921-A Having imaging and printout layers containing small doped silver halide grains at specified dopant level and third set thereof distributed in printout layer or separate protective layer EASTMAN KODAK COMPANY (US) 1994-12-13 US disclosed
EP-0609947-A1 High-contrast photographic elements with improved print-out capability EASTMAN KODAK COMPANY (US) 1994-08-10 EP disclosed
US-5279933-A Black and white photography EASTMAN KODAK COMPANY (US) 1994-01-18 US disclosed
EP-0233396-B1 SILVER HALIDE PHOTOGRAPHIC EMULSIONS WITH NOVEL GRAIN FACES (4) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-07-31 EP disclosed
US-4724200-A CRYSTAL STRUCTURE EASTMAN KODAK COMPANY (US) 1988-02-09 US disclosed
EP-0233396-A2 Silver halide photographic emulsions with novel grain faces (4) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-08-26 EP disclosed
US-4680255-A Emulsions and photographic elements containing silver halide grains having tetrahexahedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4680256-A Emulsions and photographic elements containing silver halide grains having trisoctahedra crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed
US-4680254-A Emulsions and photographic elements containing silver halide grains having hexoctamedral crystal faces EASTMAN KODAK COMPANY (US) 1987-07-14 US disclosed