SCHEMBL5197330

SCHEMBL5197330

CCc1c(C)nc2ncnn2c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
HSD17B10 Q99714 1/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
HTT P42858 3/20 0.51
MAPK1 P28482 1/20 0.51
MAPT P10636 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
LMNA P02545 5/20 0.48
ALDH1A1 P00352 3/20 0.48
RAB9A P51151 2/20 0.48
GAA P10253 1/20 0.48
USP2 O75604 1/20 0.47
GALR3 O60755 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9770335 0.88 HSD17B10 (0.56) MEN1KMT2AHSD17B10SMN1; SMN2HTT
SCHEMBL10493808 0.84 HSD17B10 (0.50) MEN1KMT2AHSD17B10SMN1; SMN2HTT
SCHEMBL12769185 0.84 HSD17B10 (0.52) MEN1KMT2AHSD17B10SMN1; SMN2HTT
SCHEMBL10493810 0.83 HSD17B10 (0.49) MEN1KMT2AHSD17B10SMN1; SMN2HTT
SCHEMBL9770175 0.83 HSD17B10 (0.49) MEN1KMT2AHSD17B10SMN1; SMN2HTT
SCHEMBL9824149 0.83 HSD17B10 (0.46) MEN1KMT2AHSD17B10SMN1; SMN2HTT
SCHEMBL13140138 0.81 HSD17B10 (0.60) HSD17B10HTTMAPK1MAPTL3MBTL1
SCHEMBL5199168 0.79 TSHR (0.50) MEN1KMT2AHSD17B10SMN1; SMN2HTT
SCHEMBL24128962 0.77 ENPP1 (0.53) ENPP1
SCHEMBL19193508 0.77 ALDH1A1 (0.42) MEN1KMT2AHSD17B10SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP claimed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US claimed
US-4078937-A SULFUR, HYDROXYTETRAAZAINDENE FUJI PHOTO FILM CO., LTD. (JA) 1978-03-14 US claimed
EP-1217432-B1 Silver halide photographic light-sensitive material and method for processing the same FUJIFILM CORP (JP) 2007-08-15 EP disclosed
US-6593076-B2 Controlling concentration of silver hlaide emulsion and organic silver salt KONICA CORPORATION (JP) 2003-07-15 US disclosed
EP-1109060-B1 Silver halide photographic element EASTMAN KODAK CO (US) 2003-06-04 EP disclosed
US-6544718-B2 Hydrophilic colloid layer includes a disulfide or dimercapto compound of given formula; for photomechanical plate-making that exhibits ultrahigh-contrast photographic characteristics FUJI PHOTO FILM CO., LTD. (JP) 2003-04-08 US disclosed
US-20030022113-A1 Silver halide photographic light-sensitive material and method for processing same FUJI PHOTO FILM CO., LTD. 2003-01-30 US disclosed
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP disclosed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US disclosed
EP-1217432-A2 Silver halide photographic light-sensitive material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 2002-06-26 EP disclosed
US-4863843-A AROMATIC DIOL, SULFONATE MITSUBISHI PAPER MILLS, LTD. (JP) 1989-09-05 US disclosed
EP-0312959-A1 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1989-04-26 EP disclosed
EP-0122125-B1 SILVER HALIDE EMULSION KONICA CORPORATION (JP) 1987-07-15 EP disclosed
EP-0175366-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-03-26 EP disclosed
US-4565778-A COMPRISING CORE/SHELL GRAINS OF SILVER IODOBROMIDE REPENED BY A LABILE SELENIUM COMPOUND;PHOTOSENSITIVITY;ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-01-21 US disclosed
US-4542094-A HYDROXYTETRAZAINDENES AND MERCAPTO-NITROGENCONTAINING HETEROCYLIC COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-17 US disclosed
EP-0122125-A1 Silver halide emulsion KONICA CORPORATION (JP) 1984-10-17 EP disclosed
EP-0121435-A1 Silver halide photographic materials KONICA CORPORATION (JP) 1984-10-10 EP disclosed
EP-0107488-A2 Silver halide emulsions KONICA CORPORATION (JP) 1984-05-02 EP disclosed