Phthalic Acid

Phthalic Acid

SCHEMBL5198532

Cc1ccccsc(C)c(C)c1C.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
LMNA P02545 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 2/20 0.47
AKR1C3 P42330 2/20 0.47
AKR1B10 O60218 1/20 0.47
TRPA1 O75762 1/20 0.47
ABCB11 O95342 1/20 0.47
DHFR P00374 1/20 0.47
MPO P05164 1/20 0.47
CYP1A2 P05177 1/20 0.47
CHRM1 P11229 1/20 0.47
AKR1B1 P15121 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
AKR1C2 P52895 1/20 0.47
AKR1C1 Q04828 1/20 0.47
HIF1A Q16665 1/20 0.47
NAPRT Q6XQN6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL5196852 0.88 GAA (0.40) KMT2AMEN1LMNACYP3A4CYP2C9
SCHEMBL752673 0.84 TSHR (0.41) KMT2AMEN1CYP3A4TRPA1CYP1A2
Fumaric Acid SCHEMBL5198477 0.83 HCAR2 (0.42) KMT2AMEN1LMNAALOX15ALDH1A1
Maleic Acid SCHEMBL5198470 0.83 HCAR2 (0.42) KMT2AMEN1LMNAALOX15ALDH1A1
Hydrochloric Acid SCHEMBL31150435 0.82 TSHR (0.39) KMT2AMEN1CYP3A4TRPA1CYP1A2
Water SCHEMBL5196978 0.82 TSHR (0.39) KMT2AMEN1CYP3A4TRPA1CYP1A2
Hydrochloric Acid SCHEMBL154108 0.82 TSHR (0.39) KMT2AMEN1CYP3A4TRPA1CYP1A2
Sulfuric Acid SCHEMBL2110043 0.81 GAA (0.36) KMT2AMEN1LMNATRPA1ALOX15
Formic Acid SCHEMBL5197972 0.81 ALDH1A1 (0.36) KMT2AMEN1LMNATRPA1ALOX15
Hydrochloric Acid SCHEMBL3327763 0.80 TSHR (0.38) KMT2AMEN1CYP3A4TRPA1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100564341-C Method for inhibiting polymerization of acrylic acid and esters thereof using inhibitor and process for preparing compounds useful as such inhibitor ROHM & HAAS (US) 2009-12-02 CN claimed
US-7220879-B2 Method for inhibiting polymerization of (meth)acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor ROHM AND HAAS COMPANY (US) 2007-05-22 US claimed
EP-1647543-B1 A method for inhibiting polymerization of (Meth) acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor ROHM & HAAS (US) 2007-05-02 EP claimed
CN-1762965-A Method for inhibiting polymerization of acrylic acid and esters thereof using inhibitor and process for preparing compounds useful as such inhibitor ROHM & HAAS (US) 2006-04-26 CN claimed
EP-1647543-A1 A method for inhibiting polymerization of (Meth) acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor Rohm and Haas Company (US) 2006-04-19 EP claimed
US-20060074257-A1 Method for inhibiting polymerization of (meth)acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor BASS STEPHEN 2006-04-06 US claimed
CN-101168623-B Method for inhibiting polymerization of (meth) acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor ROHM & HAAS 2012-12-05 CN disclosed
CN-100564341-C Method for inhibiting polymerization of acrylic acid and esters thereof using inhibitor and process for preparing compounds useful as such inhibitor ROHM & HAAS (US) 2009-12-02 CN disclosed
CN-101168623-A Method for inhibiting polymerization of (meth) acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor ROHM & HAAS (US) 2008-04-30 CN disclosed
US-20070197785-A1 METHOD FOR INHIBITING POLYMERIZATION OF (METH) ACRYLIC ACID AND ITS ESTERS USING AN INHIBITOR AND A PROCESS FOR MAKING A COMPOUND USEFUL AS SUCH AN INHIBITOR BASS STEPHEN 2007-08-23 US disclosed
US-7253279-B1 Method for inhibiting polymerization of (METH) acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor ROHM AND HAAS COMPANY (US) 2007-08-07 US disclosed
US-7220879-B2 Method for inhibiting polymerization of (meth)acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor ROHM AND HAAS COMPANY (US) 2007-05-22 US disclosed
EP-1647543-B1 A method for inhibiting polymerization of (Meth) acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor ROHM & HAAS (US) 2007-05-02 EP disclosed
CN-1762965-A Method for inhibiting polymerization of acrylic acid and esters thereof using inhibitor and process for preparing compounds useful as such inhibitor ROHM & HAAS (US) 2006-04-26 CN disclosed
EP-1647543-A1 A method for inhibiting polymerization of (Meth) acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor Rohm and Haas Company (US) 2006-04-19 EP disclosed
US-20060074257-A1 Method for inhibiting polymerization of (meth)acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor BASS STEPHEN 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197785-A1 METHOD FOR INHIBITING POLYMERIZATION OF (METH) ACRYLIC ACID AND ITS ESTERS USING AN INHIBITOR AND A PROCESS FOR MAKING A COMPOUND USEFUL AS SUCH AN INHIBITOR MMAB, AZI2, MEP1A KMT2A 421/4885MEN1 2242/4885LMNA 3629/4885
US-20060074257-A1 Method for inhibiting polymerization of (meth)acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor MMAB, AZI2, MEP1A KMT2A 421/4885MEN1 2242/4885LMNA 3629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.