Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5197022 | 0.95 | CYP1A2 (0.55) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7821089 | 0.94 | MAPT (0.57) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7832253 | 0.94 | MAPT (0.57) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2846347 | 0.91 | MGAM (0.54) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL3867467 | 0.89 | MGAM (0.53) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17288844 | 0.87 | TRPV1 (0.48) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| Trifluoroacetic Acid SCHEMBL2850398 | 0.84 | RHOA (0.48) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20224973 | 0.83 | L3MBTL1 (0.53) | CYP1A2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6614214 | 0.82 | PDGFRB (0.50) | CYP1A2SMN1; SMN2MGAMCFTRRAB9A | |
| SCHEMBL11597016 | 0.82 | CYP1A2 (0.50) | CYP1A2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262172-B2 | Macrolides | GLAXO GROUP LIMITED (GB) | 2007-08-28 | — | — | US | disclosed |
| EP-1328535-B1 | MACROLIDES | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | disclosed |
| US-20040254124-A1 | Macrolides | PLIVA D.D. (HR) | 2004-12-16 | — | — | US | disclosed |
| EP-1328535-A1 | MACROLIDES | GLAXO GROUP LIMITED (GB) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002032917-A1 | MACROLIDES | GLAXO GROUP LIMITED (GB) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254124-A1 | Macrolides | OGFOD1, TLR7, MALT1 | CYP1A2 780/4885HDAC3 51/4885HDAC4 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.