Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20224966 | 0.85 | HDAC1 (0.46) | L3MBTL1MAPK1ALDH1A1ALOX5HDAC3 | |
| SCHEMBL20346355 | 0.84 | ALDH1A1 (0.59) | L3MBTL1MAPK1CFTRMGAMALDH1A1 | |
| SCHEMBL5199025 | 0.83 | CYP1A2 (0.60) | MAPK1CFTRMGAMHDAC3HDAC4 | |
| SCHEMBL9011265 | 0.79 | HDAC3 (0.53) | CFTRMGAMALDH1A1HDAC3HDAC1 | |
| SCHEMBL14368556 | 0.79 | TDP1 (0.61) | L3MBTL1MAPK1ALDH1A1ALOX5HDAC3 | |
| SCHEMBL17288844 | 0.79 | TRPV1 (0.48) | CFTRMGAMHDAC3HDAC4HDAC1 | |
| SCHEMBL5197022 | 0.79 | CYP1A2 (0.55) | MAPK1CFTRMGAMHDAC3HDAC4 | |
| SCHEMBL20224983 | 0.79 | L3MBTL1 (0.47) | L3MBTL1MAPK1ALDH1A1CASP1SMN1; SMN2 | |
| SCHEMBL3861037 | 0.78 | MAPT (0.52) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6614214 | 0.78 | PDGFRB (0.50) | CFTRMGAMALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180154332-A1 | HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING ION PAIRED-BONDED PHASES FOR SUPERCRITICAL FLUID CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION | 2018-06-07 | — | — | US | disclosed |