SCHEMBL5199036

SCHEMBL5199036

Oc1cc(-c2ccccc2)nc2nncn12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.51
TP53 P04637 4/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
POLB P06746 2/20 0.51
CGAS Q8N884 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NTSR1 P30989 1/20 0.41
ALDH1A1 P00352 3/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAPK10 P53779 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9452026 0.75 MEN1 (0.44) MAPTTP53SMN1; SMN2POLBCGAS
SCHEMBL5145693 0.71 UBE2M (0.42) MAPTTP53SMN1; SMN2POLBCGAS
SCHEMBL5145529 0.70 KDM4E (0.67) MAPTSMN1; SMN2POLBKDM4E
SCHEMBL29541271 0.69 ADORA2A (0.47) MAPTPOLBMEN1KMT2AALDH1A1
SCHEMBL5143556 0.69 ALDH1A1 (0.44) MAPTTP53SMN1; SMN2POLBMEN1
SCHEMBL11475707 0.68 HPGD (0.44) MAPTTP53SMN1; SMN2POLBCGAS
SCHEMBL5200396 0.68 KDM4E (0.46) MAPTTP53SMN1; SMN2MEN1KMT2A
SCHEMBL5146982 0.68 KDM4E (0.69) MAPTTP53SMN1; SMN2POLBALDH1A1
SCHEMBL5145554 0.67 KDM4E (0.43) MAPTTP53SMN1; SMN2KDM4EADORA2A
SCHEMBL12439612 0.67 FLT3 (0.47) MAPTTP53SMN1; SMN2POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP claimed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US claimed
US-4078937-A SULFUR, HYDROXYTETRAAZAINDENE FUJI PHOTO FILM CO., LTD. (JA) 1978-03-14 US claimed
EP-1217432-B1 Silver halide photographic light-sensitive material and method for processing the same FUJIFILM CORP (JP) 2007-08-15 EP disclosed
US-6593076-B2 Controlling concentration of silver hlaide emulsion and organic silver salt KONICA CORPORATION (JP) 2003-07-15 US disclosed
EP-1109060-B1 Silver halide photographic element EASTMAN KODAK CO (US) 2003-06-04 EP disclosed
US-6544718-B2 Hydrophilic colloid layer includes a disulfide or dimercapto compound of given formula; for photomechanical plate-making that exhibits ultrahigh-contrast photographic characteristics FUJI PHOTO FILM CO., LTD. (JP) 2003-04-08 US disclosed
US-20030022113-A1 Silver halide photographic light-sensitive material and method for processing same FUJI PHOTO FILM CO., LTD. 2003-01-30 US disclosed
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP disclosed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US disclosed
EP-1217432-A2 Silver halide photographic light-sensitive material and method for processing the same FUJI PHOTO FILM CO., LTD. (JP) 2002-06-26 EP disclosed
US-4830955-A ANTIFOGGING AGENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-05-16 US disclosed
EP-0312959-A1 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1989-04-26 EP disclosed
EP-0122125-B1 SILVER HALIDE EMULSION KONICA CORPORATION (JP) 1987-07-15 EP disclosed
EP-0175366-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-03-26 EP disclosed
US-4565778-A COMPRISING CORE/SHELL GRAINS OF SILVER IODOBROMIDE REPENED BY A LABILE SELENIUM COMPOUND;PHOTOSENSITIVITY;ANTIFOGGING AGENTS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-01-21 US disclosed
US-4542094-A HYDROXYTETRAZAINDENES AND MERCAPTO-NITROGENCONTAINING HETEROCYLIC COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-17 US disclosed
EP-0122125-A1 Silver halide emulsion KONICA CORPORATION (JP) 1984-10-17 EP disclosed
EP-0121435-A1 Silver halide photographic materials KONICA CORPORATION (JP) 1984-10-10 EP disclosed
EP-0107488-A2 Silver halide emulsions KONICA CORPORATION (JP) 1984-05-02 EP disclosed